Curriculum Vitae
Jan Florian Kern
Molecular Biophysics and Integrated Bioimaging Division
Lawrence Berkeley National Laboratory
Institutional address:
Lawrence Berkeley National Laboratory
One Cyclotron Road, MS 66-326
Berkeley, CA 94720
Phone: 510-486-4330
e-mail: jfkern@lbl.gov
Webpage: http://biosciences.lbl.gov/profiles/jan-florian-kern/
Education:
Oct 1992 - Mar 1993 History of Science and Technology at the Technical University Berlin (TU Berlin), Germany
Apr 1993 – Aug 1999 Chemistry (Diploma) at the Technical University Berlin
Oct 1995 - Jul 1996 Diploma in Chemistry (with distinction), University of Kent, Canterbury, UK
Oct 1998 - Aug 1999 Diploma thesis (with distinction) ‘Crystallisation of Photosystem I under influence of normal and reduced gravitation’ AG Fromme/Witt, Max Volmer Laboratory for Biophysical Chemistry, TU Berlin
Jan 2000 – Feb 2005 PhD Thesis (with distinction), ‘Structural and functional investigations of Photosystem II from Thermosynechococcus elongatus’ in the groups of Fromme/Witt and Zouni/Irrgang at the Max Volmer Laboratory, TU Berlin
Oct 1996 - Dec 1996 Student assistant in the SFB 312 with Prof. Rumberg, MVL, TU Berlin
Apr 1997 - Aug 1999 Student assistant for teaching Math for Chemist and Basics of Physical Chemistry and in the German Science Ministry Project ‘Interconnected Chemistry Curriculum’ (Prof. Ziessow, Chemistry, TU Berlin)
Jan 2000 - Dec 2002 Scientific assistant in the SFB 498, TP C3 (Fromme/Witt), MVL, TU Berlin
Jan 2003 - Dec 2004 Scientific assistant in the SFB 498, TP C7 (Zouni/Irrgang), MVL, TU Berlin
Jan 2005 - Feb 2005 Scientific assistant in the SFB 498, TPA4 (Saenger), Institut für Chemie, Freie Universität Berlin
Mar 2005 - Oct 2008 Scientific assistant in the SFB 498, TP C7 (Zouni), MVL, TU Berlin
Nov 2008 - Oct 2010 Feodor Lynen Postdoctoral Fellow (Humboldt Foundation) with K. Sauer and V. Yachandra at Lawrence Berkeley National Laboratory, University of California, Berkeley, CA.
Nov 2010 – May 2012 Postdoctoral Fellow with V. Yachandra at Lawrence Berkeley National Laboratory, Berkeley, and U. Bergmann at LCLS, SLAC, Stanford
May 2012 – Sept 2015 Career Track (Term) Research Scientist employed jointly by LBNL, Berkeley, and LCLS/SLAC, Stanford
Sept 2015 – March 2019 Career Research Scientist at LBNL, Berkeley
March 2016 – Dec 2016 jointly employed by LBNL, Berkeley and LCLS/SLAC, Stanford
Since March 2019 Staff Scientist at LBNL, Berkeley
Deposited scientific datasets in public repositories:
Protein Data Bank (www.rcsb.org): 32 entries
Accession codes: 6DHE, 6DHF, 6DHO, 6DHG, 6DHH, 6DHP, 5MX2, 5MG0, 5MG1, 5KAF, 5KAI, 5TIS, 5F81, 5HQD, 5HL4, 5BR8, 4PJ0, 4TNH, 4TNI, 4TNJ, 4TNK, 4TNL, 4V62, 4V82, 4OW3, 4IXQ, 4IXR, 4FBY, 3KZI, 2AXT, 1W5C, 1FE1
Coherent X-ray Diffraction Data Bank (www.cxidb.org): 1 entry
Accession code ID23
Awards and Stipends
- Feodor Lynen Postdoc Stipend of the Alexander von Humboldt Foundation (2008-2010)
- Richard Malkin Award for best Post Doc contribution at the 18th Western Photosynthesis Conference (2009)
Funding and experimental time awarded:
- National Institutes of Health NIGMS grant over 4 years (9/16/2017-6/30/2021)
- Department of Energy, Office of Science, Basic Energy Sciences, Field Work Proposal over 3 years in the “Photosynthetic Systems” program (8/1/2018-7/31/2021)
- Experimental time awarded at the SACLA user facility, Japan (October 2017, June 2018, February 2020)
- Experimental time awarded at the PAL XFEL user facility, Korea (October 2019)
- Experimental time awarded at the Spallation Neutron Source at Oak Ridge National Laboratory, Tennessee (November 2016 and November 2018)
- Experimental time awarded at the LCLS user facility, SLAC, Stanford (Jul 2015, Jul 2016, October 2016, May 2018, December 2018)
Reviewing activity
Reviewed scientific manuscripts for a variety of journals including:
Advances in Physics, Biochemistry, Chemical Communications, Chemical Sciences, Energy & Environmental Science, Journal Applied Crystallography, Journal of Biological Chemistry, Nature Communications, PLOSone, Proceedings of the National Academy of Sciences USA
Reviewed research grant proposals for Laboratory Director Research Development funds at the Stanford National Accelerator Laboratory, SLAC (Apr 2016, Apr 2017, May 2018), beam time proposals for the Oak Ridge Spallation Neutron Source (Oct 2018, Oct 2019), and Field Work Proposals to the Department of Energy, Office of Science, Basic Energy Science (DOE-BES) in the program of “Physical Biosciences” (Mar 2017), for the “Research at the Frontiers of XFEL Ultrafast Chemical and Materials Sciences” funding opportunity (June 2018) and for the Early Career Awards (March 2019). Member of the design review committee for the NEH 2.2 Liquid Jet End Station Design (October 2017, September 2018) for the LCLS-II facility at SLAC. Reviewed poster contribution and selected talks as chair of a micro symposium in the 24th International Union of Crystallography Conference, Aug. 2017, Hyderabad, India.
Membership in Scientific organizations:
American Association for the Advancement of Sciences, AAAS
International Society of Photosynthesis Research, ISPR
American Crystallographic Association, ACA
Publications and Invited Talks
As of January 14th 2020
Google Scholar Profile: http://scholar.google.com/citations?user=F02wtH8AAAAJ&hl=en&oi=sra
h-index: 39
total citations: 11140
ReserachGate Profile:
https://www.researchgate.net/profile/Jan_Kern
RG score: 40.87 Reads: 17231 Citations: 8856
ORCID ID 0000-0002-7272-1603
ResearcherID: G-2586-2013
Journal and Book Contributions (*denotes equal contribution, +denotes corresponding author)
2020
83. N. K. Sauter+, J. Kern, J. Yano, J. M. Holton, Towards the spatial resolution of metalloprotein charge states by detailed modeling of XFEL crystallographic diffraction, Acta Cryst. D, in press (2020)
82. E.S. Burgie, J.A. Clinger, M.D. Miller, A.S. Brewster, P. Aller, A. Butryn, F.D. Fuller, S. Gul, I.D. Young, C.C. Pham, I.-S. Kim, A. Bhowmick, L.J. O’Riordan, K.D. Sutherlin, J.V. Heinemann, A.Batyuk, R. Alonso-Mori, M. Hunter, J.E. Koglin, J. Yano, V. Yachandra, N.K. Sauter, A.E. Cohen, J. Kern+, A.M. Orville+, G.N. Phillips Jr+, R.D. Vierstra+, Photoreversible interconversion of a phytochrome photosensory module in the crystalline state, Proc. Natl. Acad. Sci. U S A 117 (2020) 300-307.
2019
81. J. Kern, F. Müh, A. Zouni, Structural studies on tetrapyrrole containing proteins enabled by femtosecond X-ray pulses Advances. Bot. Res. (2019) Vol 98, pp 33-67, (DOI: 10.1016/bs.abr.2019.04.003)
80. R. Chatterjee, C. Weninger, A. Loukianov, S. Gul, F. D. Fuller, M. H. Cheah, T. Fransson, S. Nelson, S. Song, A. Britz, J. Messinger, U. Bergmann, R. Alonso-Mori, V. K. Yachandra+, J. Kern+, J. Yano+, XANES and EXAFS of Dilute Solutions of Transition Metals at XFELs, J. Synchr. Rad. 28 (2019) (DOI:10.1107/S1600577519007550)
79. R. Chatterjee, L. Lassalle, S. Gul, F. D. Fuller, I. D. Young, M. Ibrahim, C. de Lichtenberg, M. H. Cheah, A. Zouni, J. Messinger+, V. K. Yachandra+, J.Kern+, J. Yano+, Structural Isomers of the S2 state in Photosystem II: Do they exist at room temperature and are they important for function? Physiol Plantarum 166 (2019), 60-72 (DOI: 10.1111/ppl.12947)
2018
78. J. Kern, R. Chatterjee*, I.D. Young*, F.D. Fuller*, L. Lassalle, M. Ibrahim, S. Gul, T. Fransson, A.S. Brewster, R. Alonso-Mori, R. Hussein, M. Zhang, L. Douthit, C. de Lichtenberg, M.H. Cheah, D. Shevela, J. Wersig, I. Seufert, D. Sokaras, E. Pastor, C. Weninger, T. Kroll, R.G. Sierra, P. Aller, A. Butryn, A.M. Orville, M. Liang, A. Batyuk, J.E. Koglin, S. Carbajo, S. Boutet, N.W. Moriarty, J.M. Holton, H. Dobbek, P.D. Adams, U. Bergmann, N.K. Sauter, A. Zouni+, J. Messinger+, J. Yano+, V.K. Yachandra+, Structures of the intermediates of Kok’s photosynthetic water oxidation clock, Nature 563 (2018), 421–425 (DOI: 10.1038/s41586-018-0681-2)
77. J. Yano, J. Kern, Update on Photosystem II complex, in Encyclopedia of Inorganic and Bioinorganic Chemistry (R. A. Scott (ed.)), Willey (2018) (DOI: 10.1002/9781119951438.eibc2619)
76. M. Kubin, M. Guo, T. Kroll, H. Löchel, E. Källman, M.L. Baker, R. Mitzner, S. Gul, J. Kern, A. Föhlisch, A. Erko, U. Bergmann, V. Yachandra, J. Yano, M. Lundberg+, P. Wernet+, Probing the Oxidation State of Transition Metal Complexes: A Case Study on How Charge and Spin Densities Determine Mn L-Edge X-ray Absorption Energies, Chemical Science 9 (2018), 6813 (DOI: 10.1039/C8SC00550H)
75. M. Kubin, M. Guo, M. Ekimova, E. Källman, J. Kern, V.K. Yachandra, J. Yano, E.T.J. Nibbering+, M. Lundberg+, P. Wernet+, Cr L-edge X-ray Absorption Spectroscopy of CrIII(acac)3 in Solution with Measured and Calculated Absolute Absorption Cross Sections, J. Phys. Chem. B 22 (2018) 7375-7384 (DOI: 10.1021/acs.jpcb.8b04190)
74. T. Fransson, R. Chatterjee, F.D. Fuller, S. Gul, C. Weninger, D. Sokaras, T. Kroll, R. Alonso-Mori, U. Bergmann+, J. Kern+, V.K. Yachandra+, J. Yano+, X-ray Emission Spectroscopy as an In Situ Diagnostic Tool for X-ray Crystallography of Metalloproteins Using an X-ray Free Electron Laser, Biochemistry 57 (2018), 4629-4637 (DOI: 10.1021/acs.biochem.8b00325)
73. M. Kubin, J. Kern, M. Guo, E. Källman, R. Mitzner, V.K. Yachandra, M. Lundberg, J. Yano+, P. Wernet+, X-ray-Induced Sample Damage at the Mn L-edge Energy: A Case Study for Soft X-ray Spectroscopy of Transition Metal Complexes in Solution, Phys. Chem. Chem. Phys. 20 (2018), 16817-16827 (DOI: 10.1039/C8CP03094D)
72. A. Kölsch+, M. Hejazi, K.R. Stieger, S.C. Feifel, J.F. Kern, F. Müh, F. Lisdat, H. Lokstein, A. Zouni+, Insights into the binding behavior of native and non-native cytochromes to Photosystem I from Thermosynechococcus elongatus, J. Biol. Chem. 293 (2018), 9090-9100 (DOI: 10.1074/jbc.RA117.000953)
71. M. Kubin, M. Guo, M. Ekimova, M. Baker, T. Kroll, E. Källman, J. Kern, V.K. Yachandra, J. Yano, E.T.J. Nibbering+, M. Lundberg+, P. Wernet+, Direct Determination of Absolute Absorption Cross Sections at the L-Edge of Dilute Mn Complexes in Solution using a Transmission Flatjet, Inorg. Chem. 57 (2018), 5449–5462 (DOI: 10.1021/acs.inorgchem.8b00419)
70. T. Kroll+, C. Weninger+, R. Alonso-Mori, D. Sokaras, D. Zhu, L. Mercadier, V. P. Majety, Agostino Marinelli, A. Lutman, M. Guetg, F.-J. Decker, S. Boutet, A. Aquila, J. Koglin, J. Koralek, D.P. DePonte, J. Kern, F.D. Fuller, E. Pastor, T. Fransson, Y. Zhang, J. Yano, V.K. Yachandra, N. Rohringer+, U. Bergmann+, Stimulated X-ray Emission Spectroscopy in Transition Metal Complexes, Phys. Rev. Lett. 120 (2018), 133203 (DOI: 10.1103/PhysRevLett.120.133203)
69. J.D. Koralek+, J.B. Kim, P. Brůža, C. Curry, Z. Chen, H.A. Bechtel, A.A. Cordones, P. Sperling, J.F.Kern, S.P. Moeller, S.H. Glenzer, D.P. DePonte, Generation and characterization of ultrathin free-lowing liquid sheets, Nat. Comm. 9 (2018) 1353 (DOI: 10.1038/s41467-018-03696-w)
68. R. Hussein+, M. Ibrahim, R. Chatterjee, L. Coates, F. Müh, V.K. Yachandra, J. Yano, J. Kern, H. Dobbek, A. Zouni+, Optimizing Crystal Size of Photosystem II by Macroseeding: Towards Neutron Protein Crystallography, Crystal Growth & Design 18 (2018), 85-94 (DOI: 10.1021/acs.cgd.7b00878)
2017
67. R. Alonso-Mori, J. Kern, Damage-free Electronic and Geometric Structure Determination of Metalloproteins, In: X-Ray Free Electron Lasers: Applications in Materials, Chemistry and Biology (U. Bergmann, V.K. Yachandra, J. Yano (eds.)), Royal Society of Chemistry (2017) pp 141-170 (DOI: 10.1039/9781782624097-00141)
66. M. Kubin, J. Kern, S. Gul, T. Kroll, R. Chatterjeeb, H. Löchel, F. D. Fuller, R. G. Sierra, W. Quevedo, C. Weniger, J. Rehaneke, A. Firsov, H. Laksmono, C. Weninger, R. Alonso-Mori, D. L. Nordlund, B. Lassalle-Kaiser, J. M. Glownia, J. Krzywinski, S. Moeller, J. J. Turner, M. P. Minitti, G. L. Dakovski, S. Koroidov, A. Kawde, J. S. Kanady, E. Y. Tsui, S. Suseno, Z. Han, E. Hill, T. Taguchi, A. S. Borovik, T. Agapie, J. Messinger, A. Erko, A. Föhlisch, U. Bergmann+, R. Mitzner, V. K. Yachandra+, J. Yano+, P. Wernet+, Soft X-ray Absorption Spectroscopy of Metalloproteins and High-Valent Metal-Complexes at Room Temperature Using Free-Electron Lasers, Structural Dynamics 4 (2017), 054307 (DOI: 10.1063/1.4986627)
65. M Zhang, M. Bommer, R. Chatterjee, R. Hussein, J. Yano, H. Dau+, J. Kern+, H. Dobbek+, A. Zouni+, Structural insights into the light-driven auto-assembly process of the water-oxidizing Mn4CaO5-cluster in photosystem II, eLife 6 (2017), e26933 (DOI: 10.7554/eLife.26933)
64. B. Lassalle-Kaiser, S. Gul, J. Kern, V.K. Yachandra, J. Yano+, In situ/operando studies of electrocatalysts using hard X-ray spectroscopy, J. Electr. Spect. 221 (2017), 18-27 (DOI: 10.1016/j.elspec.2017.05.001)
63. F.D. Fuller*, S. Gul*, R. Chatterjee, E.S. Burgie, I.D. Young, H. Lebrette, V. Srinivas, A.S. Brewster, T. Michels-Clark, J.A. Clinger, B. Andi, M. Ibrahim, E. Pastor, C. de Lichtenberg, R. Hussein, C.J. Pollock, M. Zhang, C.A. Stan, T. Kroll, T. Fransson, C. Weninger, M. Kubin, P. Aller, L. Lassalle, P. Bräuer, M.D. Miller, M. Amin, S. Koroidov, C.G. Roessler, M. Allaire, R.G. Sierra, P.T. Docker, J.M. Glownia, S. Nelson, J.E. Koglin, D. Zhu, M. Chollet, S. Song, H. Lemke, M. Liang, D. Sokaras, R. Alonso-Mori, A. Zouni, J. Messinger, U. Bergmann, A.K. Boal, J.M. Bollinger Jr, C. Krebs, M. Högbom, G.N. Phillips Jr, R.D. Vierstra, N.K. Sauter, A.M. Orville, J. Kern+, V.K. Yachandra+, J. Yano+, Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers, Nat. Methods 14 (2017), 443-449 (DOI: 10.1038/nmeth.4195)
2016
62. I.D. Young*, M. Ibrahim*, R. Chatterjee*, S. Gul, F.D. Fuller, S. Koroidov, A.S. Brewster, R. Tran, R. Alonso-Mori, T. Kroll, T. Michels-Clark, H. Laksmono, R.G. Sierra, C.A. Stan, R. Hussein, M. Zhang, L. Douthit, M. Kubin, C. de Lichtenberg, L. Vo Pham, H. Nilsson, M.H. Cheah, D. Shevela, C. Saracini, M.A. Bean, I. Seuffert, D. Sokaras, T.-C. Weng, E. Pastor, C. Weninger, T. Fransson, L. Lassalle, P. Bräuer, P. Aller, P.T. Docker, B. Andi, A.M. Orville, J.M. Glownia, S. Nelson, M. Sikorski, D. Zhu, M.S. Hunter, T.J. Lane, A. Aquila, J.E. Koglin, J. Robinson, M. Liang, S. Boutet, A.Y. Lyubimov, M. Uervirojnangkoorn, N.W. Moriarty, D. Liebschner, P.V. Afonine, D.G. Waterman, G. Evans, P. Wernet, H. Dobbek, W.I. Weis, A.T. Brunger, P.H. Zwart, P.D. Adams, A. Zouni+, J. Messinger+, U. Bergmann, N.K. Sauter, J. Kern, V.K. Yachandra+, J. Yano+, Structure of photosystem II and substrate binding at room temperature, Nature 540 (2016) 453-457 (DOI: 10.1038/nature20161)
61. R. Alonso-Mori, U. Bergmann, A. S. Brewster, S. Boutet, R. Chatterjee, H. M. Frei, F. D. Fuller, E. Goggins, S. Gul, H. Fukuzawa, M. Ibrahim, T. Katayama, T. Kroll, X. Kimura, M. Liang, B. A. McClure, J. Messinger, K. Motomura, K. Nagaya, C. Saracini, N. K. Sauter, R. G. Sierra, D. Sokaras, T. Togashi, K. Ueda, W.W. Weare, T.-C. Weng, M. Yabashi, V.K. Yachandra, I.D. Young, A. Zouni, J. Kern+, J. Yano+, Towards Characterization of Photo-Excited Electron Transfer and Catalysis in Natural and Artificial Systems Using XFELs, Faraday Discuss. 194, 621-638 (2016) (DOI: 10.1039/C6FD00084C)
60. T. Kroll, J. Kern, M. Kubin, D. Ratner, S. Gul, F.D. Fuller, H. Löchel, J. Krzywinski, A. Lutman, Y. Ding, G.L. Dakovski, S. Moeller, J.J. Turner, R. Alonso-Mori, D.L. Nordlund, J. Rehanek, C. Weniger, A. Firsov, M. Brzhesinskaya, R. Chatterjee, B. Lassalle-Kaiser, R.G. Sierra, H. Lakshmono, E. Hill, A. Borovik, A. Erko, A. Föhlisch, R. Mitzner, V.K. Yachandra, J. Yano, P. Wernet, U. Bergmann+, X-ray absorption spectroscopy using a self-seeded soft X-ray Free-Electron Laser, Optics Express 24 (2016) 22469-22480 (DOI: 10.1364/OE.24.022469)
59. R. Chatterjee, G. Han, J. Kern, S. Gul, F.D. Fuller, A. Garachtchenko, I.D. Young, T.-C. Weng, D. Nordlund, R. Alonso-Mori, U. Bergmann, D. Sokaras, M. Hatakeyama, V.K. Yachandra+, J. Yano+, Structural changes correlated with magnetic spin state isomorphism in the S2 state of the Mn4CaO5 cluster in the oxygen evolving complex of photosystem II, Chem. Sci. 7 (2016) 5236-5248 (DOI: 10.1039/c6sc00512h)
58. N.K. Sauter+, N. Echols, P.D. Adams, P.H. Zwart, J. Kern, A.S. Brewster, S. Koroidov, R. Alonso-Mori, A. Zouni, J. Messinger, U. Bergmann, J. Yano, V.K. Yachandra+, No observable conformational changes in PSII, Nature 553 (2016) E1-E2 (DOI: 10.1038/nature17983)
57. C.G. Roessler, R. Agarwal, M. Allaire+, R. Alonso-Mori, B. Andi, J.F.R. Bachega, M. Bommer, A.S. Brewster, M.C. Browne, R. Chatterjee, E. Cho, A.E. Cohen, M. Cowan, S. Datwani, V.L. Davidson, J. Defever, B. Eaton, R. Ellson, Y. Feng, L.P. Ghislain, J.M. Glownia, G. Han, J. Hattne, J. Hellmich, A. Héroux, M. Ibrahim, J. Kern, A. Kuczewski, H.T. Lemke, P. Liu, L. Majlof, W.M. McClintock, S. Myers, S. Nelsen, J. Olechno, A.M. Orville+, N.K. Sauter, A.S. Soares+, S.M. Soltis, H. Song, R.G. Stearns, R. Tran, Y. Tsai, M. Uervirojnangkoorn, C.M. Wilmot, V. Yachandra, J. Yano, E.T. Yuk, D. Zhu, A. Zouni, Acoustic injectors for drop-on-demand serial femtosecond crystallography, Structure 24 (2016) 631–640 (DOI: 10.1016/j.str.2016.02.007)
56. E.L. Baxter, L. Aguila, R. Alonso-Mori, C.O. Barnes, C.A. Bonagura, W. Brehmer, A.T. Brunger, G. Calero, T.T. Caradoc-Davies, R. Chatterjee, W.F. Degrado, J.S. Fraser, M. Ibrahim, J. Kern, B.K. Kobilka, A.C. Kruse, K.M. Larsson, H.T. Lemke, A.Y. Lyubimov, A. Manglik, S.E. McPhillips, E. Norgren, S.S. Pang, S.M. Soltis, J. Song, J. Thomaston, Y. Tsai, W.I. Weis, R.A. Woldeyes, V. Yachandra, J. Yano, A. Zouni, A.E. Cohen+, High-density grids for efficient data collection from multiple crystals, Acta Cryst. D72 (2016) 2-11 (DOI: 10.1107/S2059798315020847)
55. R.G. Sierra+, C. Gati, H. Laksmono, E. H. Dao, S. Gul, F. Fuller, J. Kern, R. Chatterjee, M. Ibrahim, A.S. Brewster, I.D. Young, T. Michels-Clark, A. Aquila, M. Liang, M.S. Hunter, J.E. Koglin, S. Boutet, E.A. Junco, B. Hayes, M.J. Bogan, C.Y. Hampton, E.V. Puglisi, N.K. Sauter, C.A. Stan, A. Zouni, J. Yano, V.K. Yachandra, S.M. Soltis, J.D. Puglisi, H. DeMirci+, Concentric-Flow Electrokinetic Injector Enables Serial Crystallography of Ribosome and Photosystem II, Nat. Methods 13 (2016) 59-62 (DOI:10.1038/nmeth.3667)
2015
54. J. Kern+, V.K. Yachandra+, J. Yano+, Metalloprotein structures at ambient conditions and in real-time: biological crystallography and spectroscopy using X-ray free electron lasers, Curr Op Struct Biol 34 (2015) 87–98 (DOI: 10.1016/j.sbi.2015.07.014)
53. M. Ibrahim*, R. Chatterjee*, J. Hellmich, R. Tran, M. Bommer, V. K. Yachandra, J. Yano+, J. Kern+, A. Zouni+, Improvements in Serial Femtosecond Crystallography of Photosystem II by Optimizing Crystal Uniformity Using Microseeding Procedures, Structural Dynamics 2 (2015) 041705 (DOI: 10.1063/1.4919741)
52. R. Alonso-Mori+, D. Sokaras, D. Zhu, T. Kroll, M. Chollet, Y. Feng, J.M. Glownia, J. Kern, H.T. Lemke, D. Nordlund, A. Robert, M. Sikorski, S. Song, T.-C. Weng, U. Bergmann, Photon-in photon-out hard X-ray spectroscopy at the Linac Coherent Light Source, J. Synchrotron Rad. 22 (2015) 612-620 (DOI: 10.1107/S1600577515004488)
51. S. Gul, J. W. D. Ng, R. Alonso-Mori, J. Kern, D. Sokaras, E. Anzenberg, B. Lassalle-Kaiser, Y. Gorlin, T.-C. Weng, P. H. Zwart, J. Z. Zhang, U. Bergmann, V. K. Yachandra, T. F. Jaramillo+, J. Yano+, Simultaneous detection of electronic structure changes from two elements of a bifunctional catalyst using wavelength-dispersive X-ray emission spectroscopy and in situ electrochemistry, Phys. Chem. Chem. Phys. 17 (2015) 8901-8912 (DOI: 10.1039/C5CP01023C)
50. J. Yano, J. Kern, V. K. Yachandra+, H. Nilsson, S. Koroidov, J. Messinger, Light-dependent production of dioxygen in photosynthesis, In: Sustaining Life on Planet Earth: Metalloenzymes Mastering Dioxygen and Other Chewy Gases, Metal Ions in Life Sciences 15 (P.M.H. Kroneck, M.E. Sosa Torres (eds.)), Springer (2015) pp 13-43 (DOI: 10.1007/978-3-319-12415-5_2)
2014
49. J. Hellmich, M. Bommer+, A. Burkhardt, M. Ibrahim, J. Kern, A. Meents, F. Müh, H. Dobbek, A. Zouni+, Photosystem II rows-of-dimers superstructure at 2.44 Å resolution through detergent extraction from a protein crystal, Structure 22 (2014) 1607-1615 (DOI: 10.1016/j.str.2014.09.007)
48. J. Kern, R. Tran, R. Alonso-Mori, S. Koroidov, N. Echols, J. Hattne, M. Ibrahim, S. Gul, H. Laksmono, R. G. Sierra, R. J. Gildea, G. Han, J. Hellmich, B. Lassalle-Kaiser, R. Chatterjee, A. S. Brewster, C. A. Stan, C. Glöckner, A. Lampe, D. DiFiore, D. Milathianaki, A. R. Fry, M. M. Seibert, J. E. Koglin, E. Gallo, J. Uhlig, D. Sokaras, T.-C. Weng, P. H. Zwart, D. E. Skinner, M. J. Bogan, M. Messerschmidt, P. Glatzel, G. J. Williams, S. Boutet, P. D. Adams, A. Zouni, J. Messinger, N. K. Sauter, U. Bergmann+, J. Yano+, V. K. Yachandra+, Taking snapshots of photosynthetic water oxidation using femtosecond X-ray diffraction and spectroscopy, Nat. Comm. 5 (2014) 4371 (DOI: 10.1038/ncomms5371)
47. J. Kern+, J. Hattne, R. Tran, R. Alonso-Mori, H. Laksmono, S. Gul, R. G. Sierra, J. Rehanek, A. Erko, R. Mitzner, P. Wernet, U. Bergmann, N. K. Sauter, V. Yachandra, J. Yano, Methods development for diffraction and spectroscopy studies of metalloenzymes at XFELs, Phil. Trans. Royal Soc. B, 369 (2014) 20130590 (DOI: 10.1098/rstb.2013.0590)
46. R. Tran, J. Kern, J. Hattne, S. Koroidov, J. Hellmich, R. Alonso-Mori, N. K. Sauter, U. Bergmann, J. Messinger, A. Zouni, J. Yano, V. K. Yachandra+, The Mn4Ca photosynthetic water-oxidation catalyst studied by simultaneous X-ray spectroscopy and crystallography using an X-ray free electron laser, Phil. Trans. Royal Soc. B, 369: 20130324 (2014) (DOI: 10.1098/rstb.2013.0324)
45. J. Hattne, N. Echols, R. Tran, J. Kern, R. J. Gildea, A. S. Brewster, R. Alonso-Mori, C. Glöckner, J. Hellmich, H. Laksmono, R. G. Sierra, B. Lassalle-Kaiser, A. Lampe, G. Han, S. Gul, D. DiFiore, D. Milathianaki, A. R. Fry, A. Miahnahri, W. E. White, D. W. Schafer, M. M. Seibert, J. E. Koglin, D. Sokaras, T.-C. Weng, J. Sellberg, M. J. Latimer, P. Glatzel, P. H. Zwart, R. W. Grosse-Kunstleve, M. J. Bogan, M. Messerschmidt, G. J. Williams, S. Boutet, J. Messinger, A. Zouni, J. Yano, U. Bergmann, V. K. Yachandra, P. D. Adams, N. K. Sauter+, Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers, Nat. Methods, 11 (2014) 545-548 (DOI: 10.1038/nmeth.2887)
2013
44. R. Mitzner, J. Rehanek, J. Kern, S. Gul, J. Hattne, T. Taguchi, R. Alonso-Mori, R. Tran, C. Weniger, H. Schröder, W. Quevedo, H. Laksmono, R. G. Sierra, G. Han, B. Lassalle-Kaiser, S. Koroidov, K. Kubicek, S. Schreck, K. Kunnus, M. Brzhezinskaya, A. Firsov, M. P. Minitti, J. J. Turner, S. Moeller, N. K. Sauter, M. J. Bogan, D. Nordlund, W. F. Schlotter, J. Messinger, A. Borovik, S. Techert, F. M. F. de Groot, A. Föhlisch, A. Erko, U. Bergmann+, V. K. Yachandra+, P. Wernet+, J. Yano+, L-edge X-ray absorption spectroscopy of dilute systems relevant to metalloproteins using a X-ray free-electron laser, J. Phys. Chem. Letters, 4 (2013) 3641-3647 (DOI: 10.1021/jz401837f)
43. V. Krewald, B. Lassalle-Kaiser, T. T. Boron III, J. Kern, M. A. Beckwith, V. K. Yachandra, V. L. Pecoraro+, J. Yano+, F. Neese+, S. DeBeer+, The protonation states of an oxo-bridged MnIV-dimer resolved by experimental and computational Mn K pre-edge X-ray absorption spectroscopy, Inorg. Chem. 52 (2013) 12904-12914 (DOI: 10.1021/ic4008203)
42. B. Lassalle-Kaiser, T. Boron, V. Krewald, J. Kern, M. Beckwith, H. Schroeder, R. Alonso-Mori, D. Nordlund, T.C. Weng, D. Sokaras, F. Neese, U. Bergmann, V. Yachandra, S. DeBeer+, V. Pecoraro+, J. Yano+, Experimental and computational X-ray emission spectroscopy as a direct probe of protonation states in oxo-bridged MnIV-dimers relevant to redox-active metalloproteins, Inorg. Chem. 52 (2013) 12915-12922 (DOI: 10.1021/ic400821g)
41. C. Glöckner, J. Kern, M. Broser, A. Zouni+, V. Yachandra+, J. Yano+, Structural changes of the oxygen evolving complex in photosystem II during the catalytic cycle, J. Biol. Chem. 288 (2013) 22607-22620 (DOI: 10.1074/jbc.M113.476622)
40. J. Kern, R. Alonso-Mori, R. Tran, J. Hattne, R. J. Gildea, N. Echols, C. Glöckner, J. Hellmich, H. Laksmono, R. G. Sierra, B. Lassalle-Kaiser, S. Koroidov, A. Lampe, G. Han, S. Gul, D. DiFiore, D. Milathianaki, A. R. Fry, A. Miahnahri, D. W. Schafer, M. Messerschmidt, M. M. Seibert, J. E. Koglin, D. Sokaras, T. –C. Weng, J. Sellberg, M. J. Latimer, R. W. Grosse-Kunstleve, P. H. Zwart, W. E. White, P. Glatzel, P. D. Adams, M. J. Bogan, G. J. Williams, S. Boutet, J. Messinger, A. Zouni, N. K. Sauter, V. K. Yachandra+, U. Bergmann+, J. Yano+, Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature, Science 340 (2013) 491-495 (DOI: 10.1126/science.1234273)
2012
39. R. Alonso-Mori, J. Kern, R. J. Gildea, D. Sokaras, T. –C. Weng, B. Lassalle-Kaiser, R. Tran, J. Hattne, H. Laksmono, J. Hellmich, C. Glöckner, N. Echols, R. G. Sierra, D. W. Schafer, J. Sellberg, C. Kenney, R. Herbst, J. Pines, P. Hart, S. Herrmann, R. W. Grosse-Kunstleve, M. J. Latimer, A. R. Fry, M. Messerschmidt, A. Miahnahri, M. M. Seibert, P. H. Zwart, W.E. White, P.D. Adams, M. J. Bogan, S. Boutet, G. J. Williams, A. Zouni, J. Messinger, P. Glatzel, N. K. Sauter, V. K. Yachandra+, J. Yano+, U. Bergmann+, Shot-by-shot energy-dispersive X-ray emission spectroscopy using an X-ray free electron laser, Proc Natl Acad Sci U S A 109 (2012) 19103-19107 (DOI: 10.1073/pnas.1211384109)
38. R. G. Sierra, H. Laksmono, J. Kern, R. Tran, J. Hattne, R. Alonso-Mori, B. Lassalle-Kaiser, C. Gloeckner, J. Hellmich, D. W. Schafer, N. Echols, R. J. Gildea, R. W. Grosse-Kunstleve, J. Sellberg, T. A. McQueen, A. R. Fry, M. M. Messerschmidt, A. Miahnahri, M. M. Seibert, C. Y. Hampton, D. Starodub, N. D. Loh, D. Sokaras, T.-C. Weng, P. H. Zwart, P. Glatzel, D. Milathianaki, W. E. White, P. D. Adams, G. J. Williams, S. Boutet, A. Zouni, J. Messinger, N. K. Sauter, U. Bergmann, J. Yano, V. K. Yachandra, M. J. Bogan+, Nanoflow electrospinning serial femtosecond crystallography, Acta Cryst. D 68 (2012) 1584-1587 (DOI: 10.1107/S0907444912038152)
37. R. Alonso-Mori, J. Kern, D. Sokaras, T.-C. Weng, D. Nordlund, R. Tran, P. Montanez, J. Delor, V. K. Yachandra, J. Yano, U. Bergmann, A multi-crystal wavelength dispersive X-ray spectrometer, Rev Scientific Inst 83 (2012) 073114 (DOI: 10.1063/1.4737630)
36. J. Yano, J. Kern, Manganese: The Oxygen-Evolving Complex & Models. In: Encyclopedia of Inorganic and Bioinorganic Chemistry (EIBC). John Wiley & Sons, Ltd: Chichester. (2012) (DOI: 10.1002/9781119951438.eibc0121.pub2)
35. J. Kern, R. Alonso-Mori, J. Hellmich, R. Tran, J. Hattne, H. Laksmono, C. Glöckner, N. Echols, R. G. Sierra, J. Sellberg, B. Lassalle-Kaiser, R. J. Gildea, P. Glatzel, R. W. Grosse-Kunstleve, M. J. Latimer, T. A. McQueen, D. DiFiore, A. R. Fry, M. Messerschmidt, A. Miahnahri, D. W. Schafer, M. M. Seibert, D. Sokaras, T.-C. Weng, P. H. Zwart, W. E. White, P. D. Adams, M. J. Bogan, S. Boutet, G. J. Williams, J. Messinger, N. K. Sauter, A. Zouni, U. Bergmann+, J. Yano+, V. K. Yachandra+, Room Temperature Femtosecond X-ray Diffraction of Photosystem II Microcrystals, Proc Natl Acad Sci U S A 109 (2012) 9721-9726 (DOI: 10.1073/pnas.1204598109)
2011
34. M. Broser, C. Glöckner, A. Gabdulkhakov, A. Guskov, J. Buchta, J. Kern, F. Müh, H. Dau, W. Saenger+, A. Zouni+, Structural basis of cyanobacterial photosystem II inhibition by the herbicide terbutryn, J. Biol. Chem. 286 (2011) 15964-15972 (DOI: 10.1074/jbc.M110.215970)
33. J. Kern+, A. Guskov, Lipids in photosystem II: multifunctional cofactors, J. Photochem. Photobiol. B, 104 (2011) 19-34 (DOI: 10.1016/j.jphotobiol.2011.02.025)
2010
32. M. Broser, A. Gabdulkhakov, J. Kern, A. Guskov, F. Mueh, W. Saenger+, A. Zouni+, Crystal structure of monomeric photosystem II from Thermosynechococcus elongatus at 3.6 Å resolution, J. Biol. Chem. 285 (2010) 26255–26262 (DOI: 10.1074/jbc.M110.127589)
31. S. Kessen, C. Teutloff, J. Kern, A. Zouni, R. Bittl+, High-field 2H-Mims-ENDOR spectroscopy on PSII single crystals: The hydrogen bonding of YD, ChemPhysChem 11 (2010) 1275-1282 (DOI: 10.1002/cphc.200901019)
30. A. Guskov, A. Gabdulkhakov, M. Broser, C. Gloeckner, J. Hellmich, J. Kern, J. Frank, F. Mueh, W. Saenger+, A. Zouni+, Recent progress in the crystallographic studies of photosystem II, ChemPhysChem 11 (2010) 1160-1171 (DOI: 10.1002/cphc.200900901)
29. Govindjee, J. Kern, J. Messinger, J. Whitmarsh (February 2010) Photosystem II. In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. (DOI: 10.1002/9780470015902.a0000669.pub2)
2009
28. J. Kern+, A. Zouni, A. Guskov, N. Krauss, Lipids in the Structure of Photosystem I, Photosystem II and the Cytochrome b6f Complex, In: Lipids in Photosynthesis: Essential and Regulatory Functions (H. Wada; N. Murata (Eds.)) Springer (2009), pp 203-242.
27. A. Guskov*, J. Kern*, A. Gabdulkhakov, M. Broser, A. Zouni+, W. Saenger+, Cyanobacterial photosystem II at 2.9-Å resolution and the role of quinones, lipids, channels and chloride, Nature Struct Mol Biol 16 (2009) 334-342 (DOI: 10.1038/nsmb.1559)
26. A. Gabdulkhakov, A. Guskov, M. Broser, J. Kern, F. Mueh, W. Saenger+, A. Zouni+, Probing the Accessibility of the Mn4Ca Cluster in Photosystem II: Channels Calculation, Noble Gas Derivatization, and Cocrystallization with DMSO, Structure 17 (2009) 1223-1234. (DOI: 10.1016/j.str.2009.07.010)
25. T.S. Balaban+, P. Braun, C. Haettig, A. Hellweg, J. Kern, W. Saenger, A. Zouni, Preferential pathways for light-trapping involving beta-ligated chlorophylls, Biochim Biophys Acta 1787 (2009) 1254-1265. (DOI: 10.1016/j.bbabio.2009.05.010)
2008
24. S. Zein, L.V. Kulik, J. Yano, J. Kern, Y. Pushkar, A. Zouni, V.K. Yachandra, W. Lubitz, F. Neese, J. Messinger+, Focussing the view on Nature’s water-splitting catalyst, Philos Trans R Soc Lond B Biol Sci 363 (2008) 1167-1177 (DOI: 10.1098/rstb.2007.2212)
23. J. Yano, J. Kern, Y. Pushkar, K. Sauer, P. Glatzel, U. Bergmann, J. Messinger, A. Zouni, V.K. Yachandra+, High-Resolution Structure of the Photosynthetic Mn4Ca Catalyst from X-ray Spectroscopy, Philos Trans R Soc Lond B Biol Sci 363 (2008) 1139-1147 (DOI: 10.1098/rstb.2007.2209)
22. B. Loll, M. Broser, P.B. Kos, J. Kern+, J. Biesiadka, I. Vass, W. Saenger, A. Zouni, Modeling of variant copies of subunit D1 in the structure of photosystem II from Thermosynechococcus elongatus, Biol Chem 389 (2008) 609-617 (DOI: 10.1515/BC.2008.058).
2007
21. B. Loll, J. Kern+, W. Saenger, A. Zouni, J. Biesiadka, Lipids in photosystem II: interactions with protein and cofactors, Biochim Biophys Acta 1767 (2007) 509-519 (DOI: 10.1016/j.bbabio.2006.12.009)
20. R. Krivanek, J. Kern, A. Zouni, H. Dau+, M. Haumann+, Spare quinones in the QB cavity of crystallized photosystem II from Thermosynechococcus elongatus, Biochim Biophys Acta 1767 (2007) 520-527 (DOI: 10.1016/j.bbabio.2007.02.013)
19. J. Kern+, J. Biesiadka, B. Loll, W. Saenger, A. Zouni, Structure of the Mn4-Ca cluster as derived from X-ray diffraction, Photosynth Res 92 (2007) 389-405 (DOI: 10.1007/s11120-007-9173-1)
18. J. Kern+ and G. Renger+, Photosystem II: Structure and mechanism of the water:plastoquinone oxidoreductase, Photosynth Res 94 (2007) 183-202 (DOI: 10.1007/s11120-007-9201-1)
17. H. Ishikita+, B. Loll, J. Biesiadka, J. Kern, K.-D. Irrgang, A. Zouni, W. Saenger, E.W. Knapp+, Function of two b-carotenes near the D1 and D2 proteins in photosystem II dimers, Biochim Biophys Acta 1767 (2007) 79-87 (DOI: 10.1016/j.bbabio.2006.10.006).
2006
16. K. Zimmermann, M. Heck, J. Frank+, J. Kern, I. Vass, A. Zouni+, Herbicide binding and thermal stability of photosystem II isolated from Thermosynechococcus elongatus, Biochim Biophys Acta 1757 (2006) 106-114 (DOI: 10.1016/j.bbabio.2005.12.002)
15. J. Yano*, J. Kern*, K. Sauer, M.J. Latimer, Y. Pushkar, J. Biesiadka, B. Loll, W. Saenger, J. Messinger+, A. Zouni+, V.K. Yachandra+, Where water is oxidized to dioxygen: structure of the photosynthetic Mn4Ca cluster, Science 314 (2006) 821-825 (DOI: 10.1126/science.1128186)
14. C. Teutloff, S. Kessen, J. Kern, A. Zouni, R. Bittl+, High-field (94-GHz) EPR spectroscopy on the S2 multiline signal of Photosystem II, FEBS Lett 580 (2006) 3605-3609 (DOI: 10.1016/j.febslet.2006.05.039)
2005
13. A. Zouni+, J. Kern, J. Frank, T. Hellweg, J. Behlke, W. Saenger, K.D. Irrgang+, Size determination of cyanobacterial and higher plant Photosystem II by gel permeation chromatography, light scattering, and ultracentrifugation, Biochemistry 44 (2005) 4572-4581. (DOI: 10.1021/bi047685q)
12. J. Yano*, J. Kern*, K.D. Irrgang, M.J. Latimer, U. Bergmann, P. Glatzel, Y. Pushkar, J. Biesiadka, B. Loll, K. Sauer, J. Messinger+, A. Zouni+, V.K. Yachandra+, X-ray damage to the Mn4Ca complex in single crystals of photosystem II: A case study for metalloprotein crystallography, Proc Natl Acad Sci U S A 102 (2005) 12047-12052 (DOI: 10.1073/pnas.0505207102)
11. B. Loll*, J. Kern*, W. Saenger+, A. Zouni+, J. Biesiadka, Towards complete cofactor arrangement in the 3.0 Å resolution structure of photosystem II, Nature 438 (2005) 1040-1044 (DOI: 10.1038/nature04224)
10. B. Loll, J. Kern, A. Zouni, W. Saenger, J. Biesiadka, K.D. Irrgang+, The antenna system of photosystem II from Thermosynechococcus elongatus at 3.2 angstrom resolution, Photosynth Res 86 (2005) 175-184.
9. J. Kern, B. Loll, C. Lüneberg, D. DiFiore, J. Biesiadka, K.D. Irrgang, A. Zouni+, Purification, characterisation and crystallisation of photosystem II from Thermosynechococcus elongatus cultivated in a new type of photobioreactor, Biochim Biophys Acta 1706 (2005) 147-157 (DOI: 10.1016/j.bbabio.2004.10.007)
8. J. Kern, B. Loll, A. Zouni, W. Saenger, K.-D. Irrgang+, J. Biesiadka+, Cyanobacterial Photosystem II at 3.2 Å resolution - the quinone binding pockets, Photosynth Res 84 (2005) 153-159.
7. O. Kaminskaya, J. Kern, V.A. Shuvalov, G. Renger+, Exctinction coefficients of cytochromes b559 and c550 of Thermosynechococcus elongatus and cyt b559/PSII stoichiometry of higher plants, Biochim Biophys Acta 1708 (2005) 333-341 (DOI: 10.1016/j.bbabio.2005.05.002)
2004
6. J. Biesiadka+, B. Loll, J. Kern, K.-D. Irrgang and A. Zouni+, Crystal structure of cyanobacterial photosystem II at 3.2 Å resolution: a closer look at the Mn-cluster, Phys Chem Chem Phys 6 (2004) 4733-4736. (DOI: 10.1039/b406989g)
2003
5. J. Sarrou+, S. Isgandarova, J. Kern, A. Zouni, G. Renger, W. Lubitz, J. Messinger, Nitric oxide-induced formation of the S-2 state in the oxygen-evolving complex of photosystem II from Synechococcus elongatus, Biochemistry 42 (2003) 1016-1023 (DOI: 10.1021/bi026327p)
4. M. Kammel, J. Kern, W. Lubitz+, R. Bittl+, Photosystem II single crystals studied by transient EPR: the light-induced triplet state, Biochim Biophys Acta 1605 (2003) 47-54 (DOI: 10.1016/S0005-2728(03)00063-X)
2002
3. P. Fromme+, J. Kern, B. Loll, J. Biesiadka, W. Saenger, H.T. Witt, N. Krauss, A. Zouni, Functional implications on the mechanism of the function of photosystem II including water oxidation based on the structure of photosystem II, Philos Trans R Soc Lond B Biol Sci 357 (2002) 1337-1344.(DOI: 10.1098/rstb.2002.1143)
2001
2. A. Zouni, H.T. Witt, J. Kern, P. Fromme, N. Krauss, W. Saenger+, P. Orth, Crystal structure of photosystem II from Synechococcus elongatus at 3.8 Å resolution, Nature 409 (2001) 739-743 (DOI: 10.1038/35055589)
1. W. Hofbauer, A. Zouni, R. Bittl, J. Kern, P. Orth, F. Lendzian, P. Fromme, H.-T. Witt, W. Lubitz+, Photosystem II single crystals studied by EPR spectroscopy at 94 GHz: the tyrosine radical YD+, Proc Natl Acad Sci U S A 98 (2001) 6623-6628 (DOI: 10.1073/pnas.101127598)
Invited Talks at Conferences/ Invited Seminar Presentations:
2020
LCLS Structural Biology Science Review, Menlo Park, CA, USA, February 3-4 2020, “Watching enzymes at work: room temperature diffraction and spectroscopy studies utilizing femtosecond X-ray”
2019
Invited Seminar at the Chemistry Department, University of Oxford, UK, November 2019
Invited Seminar at the SFB 1078, Charitee Berlin, Germany, November 19th 2019, “Watching enzymes at work: room temperature diffraction and spectroscopy studies utilizing femtosecond X-ray pulses”
DOE Photosynthetic Systems Principal Investigators Meeting, October 21st 2019, “Visualizing Structural Dynamics in Photosynthetic Reaction Centers on the Femtosecond to Seconds Time Scale”
SSRL/LCLS Users' Meeting, Menlo Park, CA, USA, September 24-27, 2019, “Time Resolved Studies on Enzymes Using Light and Chemical Triggering and fs X-ray Pulses”
2019 ESP-IUPB World Congress, Barcelona, Spain, August 25-30 2019, “Spectroscopic and Scattering Studies of Photosystem II Utilizing fs X-ray Pulses”
18th 40th International Conference on Vacuum Ultraviolet and X-ray Physics, San Francisco, July 1-5 2019, “Spectroscopic and Scattering Studies of Photosynthetic Systems Utilizing fs X-ray Pulses”
6th Ringberg Workshop on Structural Biology with XFELs, Tegernsee, Germany, February 27-March 2 2019, “Structural and spectroscopic studies of intermediates in the water oxidizing reaction of photosystem II using XFELs“
2018
Gordon Research Conference “Metals in Biology”, Ventura, CA, USA, January 21-26 2018, “Taking Snapshots of the Water Oxidation Reaction in Photosystem II Using Crystallography and Spectroscopy at an XFEL“
Pharmacology Department Seminar, Case Western Reserve University, Cleveland, OH, USA, March 30 2018, “Studies of reaction intermediates in photosystem II and other metalloenzymes at room temperature using femtosecond X-ray pulses”
22nd Swedish Conference on Macromolecular Structure and Function, Tällberg, Sweden, June 15-18 2018, “Snapshots of the water oxidation reaction in photosystem II using crystallography and spectroscopy at an XFEL”
SSRL/LCLS User Meeting, Stanford, CA, September 27th 2018, “Transition metal L-edge spectroscopy on biological and related systems enabled by LCLS-II”
2017
Berkeley Lab Serial Crystallography Workshop, Berkeley, Feb 16-17 2017, “Challenges and promises for serial crystallography of metalloenzymes at XFELs”
24th International Union of Crystallography Conference, Hyderabad, India, August 21-28 2017, “Room temperature femtosecond X-ray crystallography of photosystem II”
Janelia Conference “Challenges in Structural Biology”, Ashburn, VA, October 15-18 2017, “Studies of reaction intermediates in photosystem II using fs X-ray pulses”
2016
BioXFEL 3rd International Conference, San Juan, Puerto Rico, January 13-15 2016 “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
Seminar at Diamond Light Source, Didcot, UK, April 5th 2016, “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
Biochemistry Department Seminar at Imperial College, London, UK, April 6th 2016, “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
17th International Congress on Photosynthesis Research, Maastricht, The Netherlands, August 7-12 2016 “Substrate binding to the OEC and mechanism of water oxidation studied by spectroscopy and room temperature fs X-ray crystallography of PSII”
12th International Conference on Biology and Synchrotron Radiation, Stanford, August 21-24 2016 “Mechanism of Water Oxidation in Photosystem II Studied by Room Temperature fs X-ray Crystallography and Spectroscopy”
ALS-CXRO Seminar, Berkeley, September 14th 2016 “Watching Photosystem II at Work: Taking Snapshots of Photosynthetic Water Oxidation with an X-ray Laser"
2015
Seminar EMBL Hamburg, Germany, May 5th 2015, “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
Workshop “Crystallography, Spectroscopy and Microscopy of photosynthetic Protein Complexes”, Szeged, Hungary, September 18-19 2015, “Combining X-ray Spectroscopy and Diffraction to Study the Catalytic Cycle of Photosystem II Using Synchrotron and XFEL Sources”
Department Seminar at Louisiana State University, Baton Rouge, LA, September 28th 2015 “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
SSRL/LCLS User Meeting, Stanford, CA, October 9th 2015, “Potential for Biological Spectroscopy in the Tender X-ray Regime”
Department Seminar at UC Riverside, Riverside, CA, October 27th 2015 “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
Workshop “THz to soft X-ray” at BESSY II, Berlin, Germany, December 7-8 2015 “Toward Molecular Movies of Metalloenzyme Catalysis Using fs X-ray Pulses – Studies on Photosystem II at LCLS”
2014
Umea Renewable Energy Meeting, Umea, Sweden, March 17-19 2014, “Taking Snapshots of Photosynthetic Water Oxidation: Combined structural and spectroscopic studies on PSII using fs X-ray pulses”
8th Radiation Damage Workshop, Hamburg, Germany, April 10-12 2014, “Combining X-ray spectroscopy and diffraction to monitor radiation damage in photosystem II at SR and XFEL sources”
American Crystallographic Association Annual Meeting 2014, Albuquerque, NM, June 24-29 2014, “Combining X-ray spectroscopy and diffraction to study the catalytic cycle of photosystem II using synchrotron and XFEL sources”
SSRL/LCLS User Meeting, Stanford, CA, October 8 2014, “Watching Photosystem II at Work Using fs X-ray Pulses”
ELI-ALPS Workshop 2014, Szeged, Hungary, October 18-21 2014, “Watching Photosystem II at Work Using fs X-ray Pulses”
2013
American Crystallographic Association Annual Meeting 2013, Honolulu, Hawaii, July 20-24 2013, “Simultaneous fs X-ray emission and X-ray diffraction measurement from micro crystals of Photosystem II”
Royal Society Meeting on “X-ray free electron lasers in biology – Techniques”, Chicheley, UK, Oct 16-17 2013, “Methods development for diffraction and spectroscopy studies at XFELS and application to Photosystem II”
Laboratory of Molecular Biology, MRC, Seminar, Cambridge, UK, Oct 22nd 2013, “Taking Snapshots of Photosynthetic Water Oxidation: Simultaneous Femtosecond X-ray Spectroscopy and Diffraction at Room Temperature Using a X-ray Free Electron Laser”
Midwestern Photosynthesis Meeting, Turkey Run, Indiana, Nov 8/9 2013, “Taking Snapshots of Photosynthetic Water Oxidation - Simultaneous Femtosecond X-ray Spectroscopy and Diffraction at Room Temperature Using a X-ray Free Electron Laser”
2012
Structural Molecular Biology Summer School 2012, SSRL/SLAC, Stanford, CA, USA, July 16-17 2012, “X-ray Emission Spectroscopy of Photosystem II and related systems”
The 70th Annual Pittsburgh Diffraction Conference, Stanford, CA, USA, Sept. 30- Oct 2 2012, “X-ray Spectroscopy and Femtosecond Diffraction of Photosystem II”
ESF-EMBO Symposium Molecular Bioenergetics of cyanobacteria: Towards System Biology Level of Understanding, Mar/Apr 2008, Sant Feliu de Guixols, Spain, ” Lipids, Quinones and Channels - current state of the structural model of cyanobacterial Photosystem II”
2011
20th Western Photosynthesis Conference, Asilomar, CA, USA, Jan 6-9 2011, „Recent progress in X-ray spectroscopy of the Mn4Ca cluster in Photosystem II“
Workshop Time Resolved X‐Ray Science at High Repetition Rate, SLAC, Stanford, CA, USA, Oct 22-23 2011, „Time Resolved X-ray studies of biological systems - Taking snapshots of the photosynthetic water oxidation reaction”
2010
Danforth Plant Center Fall Symposium 2010, St. Luis, MO, USA, Sept. 29-Oct 1st 2010, “Cyanobacterial Photosystem II at 2.9 Å Resolution”
2009
18th Western Photosynthesis Conference, Asilomar, CA, USA, Jan 8-11 2009, „Cyanobacterial Photosystem II at 2.9 Å Resolution“
14th International Conference on Biological Inorganic Chemistry, Nagoya, Japan, Jul 26 - 30 2009, „Cyanobacterial Photosystem II at 2.9 Å Resolution“
International Symposium on
Bioinorganic Chemistry, Mito, Japan, Aug 1-2 2009
„Insights into the water splitting catalyst of Photosystem II from combining
spectroscopy and structural studies“
2007
Gordon Research Conference “Metals in Biology”, Ventura, CA, USA, Jan/Feb 2007, „Refined X-ray Structure of Photosystem II at 3.0 Å Resolution“
XIV International Workshop on Plant Membrane Biology, Valencia, Spain, Jun 2007, “Lipids in the structure of Photosystem II“
International Symposium of the Collaborative Research Center Sfb-498, Berlin, Germany, Sep 2007, „Recent progress in structural and functional characterization of photosystem II”
2006
International Symposium of the SFB 429 "Signals, Sensing and Plant Primary Metabolism", Potsdam, Germany, Apr 2006, „Crystal structure of cyanobacterial Photosystem II“
38th Crystallographic Meeting/School at Erice, Italy, Jun 2006, „Structure of photosystem II“
Gordon Research Conference “Photosynthesis”, Smithfield, RI, USA, Jul 2006, „Structure of PSII at 3.0 Å Resolution“
International Conference ‘‘Photosynthesis in the Post-Genomic Era: Structure and Function of Photosystems” Pushchino, Russia, Aug 2006, “Structure of PSII at 3.0 Å Resolution”
2005
Gordon Research Conference “Photosynthesis” Smithfield, RI, USA, Jul 2005, „X-ray structure of Photosystem II“
2004
Conference: Photosynthesis and Post-genomic Era, Trois-Rivieres, Canada, Aug 2004, "Crystal structure of cyanobacterial photosystem II at 3.2 Å resolution"
13th International Photosynthesis Conference, Montreal, Canada, Aug/Sep 2004, "Crystal structure of cyanobacterial photosystem II at 3.2 Å resolution"
2002
Symposium Water in Biology, Lund, Sweden, May 2002, "Photosystem II: From Water to Oxygen"
2001
Symposium “Et.pcet:HAT:pt: 40 Years of Tunneling in Biology”, University of Pennsylvania, Philadelphia, USA, May 2-5 2001, "Structure of Photosystem II at 3.8 Å resolution"
Joint French-German Biophysics Meeting on Biophysical Aspects of Electron and Proton Transfer, Hünfeld, Germany, Oct. 2001, "Biochemical characterization and crystal structure of water oxidizing Photosystem II from Synechococcus elongatus at 3.8 Å resolution"
2000
Photosynthetic Energy Conversion TMR-Network Meeting, Athens, Greece, Nov. 2000, "Biochemical characterization and crystal structure of water oxidizing Photosystem II from Synechococcus elongatus at 3.8 Å resolution"