The confocal microscope searches for Protein 4.1 (green) in the nucleus of human fibroblast cells. Nuclear proteins are tagged in red. Yellow appears where red and green proteins overlap.
Pores embedded in nuclear membranes or an underlying lamin protein shell appear as a ring surrounding Protein 4.1.
Protein 4.1 is revealed in the interior of a nucleus stained with another nuclear matrix protein.
Large storage sites for RNA splicing proteins in the nucleus dwarf neighboring Protein 4.1.
Protein 4.1. is visible near DNA replication centers scattered throughout the nucleus.
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