LBL Currents -- August 5, 1994

LBL, Somatix sign agreement to tackle Parkinson's disease

By David Gilbert, DEGilbert@lbl.gov

LBL is going to put its medical imaging technology to work in the fight against Parkinson's disease, a debilitating illness that affects more than 800,000 people in the United States.

In a cooperative effort to study the disease, the Laboratory has signed a $2.5 million, three-year Cooperative Research and Development Agreement (CRADA) with Somatix Therapy Corp. of Alameda.

For the animal study, Somatix will genetically alter skin cells (fibroblasts) to produce dopamine, a neurotransmitter. Insufficient levels of this compound in the brain are associated with Parkinson's disease.

Once the modified fibroblasts are implanted into areas of the brain where the neurotransmitter is needed, LBL's positron emission tomography (PET) or single photon computed tomography (SPECT) scanning techniques will be used to determine if dopamine production has been restored. The PET or SPECT scans detect radiolabelled compounds that bind to cells secreting neurotransmitters. Maps of cell secretion before and after treatment can be compared to determine if new neurochemical activity is generated as a direct result of the implantation.

LBL's technology differs significantly from magnet resonance imaging (MRI), which cannot provide information on cell function, says Dr. William Jagust, a faculty researcher in the Life Sciences Division's Center for Functional Imaging. Instead, he says, MRI scans can only detect location and physical condition of implanted cells.

Jagust, also an associate professor of neurology at U.C. Davis, and Kris Bankiewicz, M.D., section head of preclinical studies in Somatix's neural program, are key investigators in the collaboration.

"Until now, our research has been aimed at using brain imaging techniques to study and diagnose Alzheimer's and other degenerative brain diseases in order to learn what has gone wrong with the brain chemistry and brain function," Jagust says. "With this new project, we're moving into the area of treatment using imaging techniques to monitor the effectiveness of gene therapy. These are early experiments that we hope will ultimately lead to effective treatments for patients suffering from Parkinson's and Alzheimer's."

LBL Director Charles Shank says the agreement with Somatix reflects the Laboratory's commitment to industrial research partnerships for the benefit of the nation. "Collaborative efforts like this, combining the dividends of LBL's 50-year investment in imaging technology with Somatix's expertise in gene therapy, offer our best hope for solving the mysteries of medical challenges like Parkinson's."

Jagust is also director and principal investigator of the U.C. Davis Alzheimer's Center a clinical program funded by the State of California and the National Institute on Aging.

Somatix, considered a leader in the field of gene therapy, also works on developing techniques that use genetically modified cells to treat diseases of the nervous system, hemophilia, and cancer.

PHOTO CAPTION -- Dr. William Jagust in the PET scan room of LBL's Center for Functional Imaging.
Photo by Steve Adams

New strategies emerge from management retreat

By Ron Kolb

Lawrence Berkeley Laboratory's scientific and administrative leadership stepped away from their day-to-day duties recently to study new ways to shape LBL's future in a more competitive research world.

Director Charles Shank invited his 22 managers and department heads to a two-day retreat in San Rafael June 20-21. There, the fundamentals of business and marketing were described as modern survival tactics in an academic-based research culture with a very different tradition. Shank said aggressive business strategies will be required to effectively advance LBL's initiatives through an increasingly difficult funding environment (see related article directly below entitled "Director's Corner").

"The biggest value of the retreat," said conferee William Barletta, director of the Accelerator and Fusion Research Division, "was to help us focus on what the people who pay for our work will need to know before they give us the cash. It's no longer sufficient to say we should get money because it's `excellent science.' They need to know what the societal and commercial benefits are."

Barletta, who is coordinating follow-up for the conference, said he and his colleagues concentrated on the development of business plans for research initiatives. These plans included assessments of scientific and technological need, competitive environments, customers, and marketing strategies -- a systematic approach historically not used at LBL.

The experience will also assist in the development of proposals for CRADA (Cooperative Research and Development Agreements) funding, Barletta added.

The Laboratory participants received direction and encouragement from several business specialists. Don Paul, president of Chevron Petroleum Technology Co. of Houston, talked about changing investment strategies for research and development. Greg Bischak, a marketing manager from Raychem Corp., reviewed the elements of a successful business plan. And Jerome Engel, Executive Director of the Lester Center for Entrepreneurship and Innovation at UC Berkeley, spoke on strategic positioning in a competitive market.

Also speaking at the retreat was Sunne McPeak, executive director of the Bay Area Economic Forum, who emphasized the importance of emerging technologies, and LBL's influence, to the future of the region's economy.

For work sessions, the conferees separated into teams and developed business plans for four sample exercises: an environmental remediation biotechnology consortium, a research and analysis program for California environmental hazards, a beamlines initiative for the Advanced Light Source, and a molecular design institute.

Five action steps emerged from the process:

In addition to Shank and Barletta, the conferees included Sally Benson, Klaus Berkner, Mina Bissell, Ed Burgess, Bob Cahn, Elton Cairns, Mike Chartock, Daniel Chemla, Rod Fleishman, Charles Harris, Sung-Hou Kim, Brian Kincaid, Stu Loken, David McGraw, Mohandas Narla, Pat Oddone, Pier Oddone, Harry Reed, Glenn Seaborg, James Symons, and Glenn Woods.

Director's Corner

By Charles V. Shank

As the story above describes, our Laboratory management assembled for a retreat in mid-June to discuss the ways in which we build new programs and initiatives at LBL. With the many changes in the Department of Energy and new questions arising in Congress about the support of science, it is important that we all acquire new skills that will enhance the success of our efforts.

We took a first step last year with the completion of the Laboratory Strategic Plan. This plan is the touchstone for building a new program at LBL. It contains a snapshot of LBL's special capabilities which we believe will provide an advantage for us in the competition for funds to build our program.

The plan also lays out a strategy that identifies partnerships as an increasingly important component of building new initiatives. We have had a historic partnership with the University of California, and we expect this relationship to be a very important part of our future. What is new is the realization that we need to expand our partnership base to include industry, other laboratories, and possibly other agencies of government.

This laboratory has prided itself on a tradition of scientific excellence as the basis for its success. As we move into the future, this excellence will remain the underpinning of all our efforts. Unfortunately, scientific prowess alone is insufficient to succeed in the intensely competitive arena in which we currently find ourselves.

We have to assemble a project or a program plan that clearly elucidates our goals and objectives. We need to understand and explain the value of our research and who will benefit. We must have a management plan that communicates our ability to succeed in making good on promised deliverables. We must look carefully at our successes, such as the construction of the Advanced Light Source, and build a record of achievement.

At our retreat, we were quite fortunate to receive the advice and guidance of a number of experts from academia and industry, including Don Paul of Chevron, Greg Bischak of Raychem, and Jerome Engel of UC Berkeley's Haas School of Management. We took the opportunity to bring new perspectives to a number of Laboratory initiatives, including the Advanced Light Source Beamline Initiative, the Molecular Design Initiative, and a new initiative focused on bioremediation. In each instance, we looked at the scientific case for the initiative, examined the match with core capabilities outlined in our Strategic Plan, analyzed the market and potential customers for the work, explored the role of potential partnerships, and developed a description of the benefits to be derived from the research.

In the coming week, the Division Directors will be proposing, discussing and analyzing major intiatives to be supported by Laboratory-Directed Research and Development funds. The skills acquired during our retreat will be used to help prioritize our investment in these efforts.

LBL Summer lecture series

Mina Bissell, Director of the Life Sciences Division, will be the fifth and final speaker in this year's Summer Lecture Series. For many years, Bissell has probed questions related to cell differentiation. She is well known for her pioneering work in the study of gene expression and regulation of tissue-specific functions in normal and malignant cells.

Her talk, "Why Do Normal Cells Remember Who They Are, and Cancer Cells Forget?" will begin at noon on Wednesday, Aug. 10, in the Bldg. 50 auditorium.

All Lab employees and guests are invited to attend the lecture. For more information, contact the Public Information Department at X4015.

Wednesday Aug.10 at noon, Bldg. 50 Aud.

"Why Do Normal Cells Remember Who They Are, and Cancer Cells Forget?" Mina Bissell, Director, Life Sciences Division

UC says no to VERIP for PERS employees

UC President Jack Peltason issued a brief statement on August 3 about the Public Employees Retirement System that "precludes any VERIP-type program for PERS members at all campuses, laboratories, and the Office of the President." VERIP is the University's Voluntary Early Retirement Incentive Program.

Peltason's message, directed to chancellors, laboratory directors, and vice-presidents, indicated that this decision was reached after detailed discussions on the issue, and that the University "would not proceed with such a program."

N e w s W i r e

IN PRINT:

John Clarke, a physicist in the Materials Sciences Division, is the author of a feature article in the August 1994 issue of Scientific American on SQUIDs (Superconducting Quantum Interference Devices). Clarke, who is also a UC Berkeley professor, has spent most of his 25-year career studying superconductivity, particularly the development and application of SQUIDs, which are the most sensitive detectors for measuring changes in magnetic fields available to science.

What's Happening in Chemistry, the American Chemical Society's annual compendium of selected research highlights in the field of chemical sciences, which is aimed at journalists and educators, features work at LBL in two articles. One article discusses the naming of element 106 "seaborgium" after Associate Director at Large Glenn Seaborg, and describes the discovery and confirmation of 106 at the Laboratory. The second article discusses the synthesis of a carbon nitride material that is harder than diamond, and based on the theoretical predictions of Marvin Cohen, a physicist in the Materials Sciences Division. The work of other LBL researchers is cited as additional references for several other highlights.

SEABORG PUBLISHES AGAIN:

Two books by LBL Associate-Director-at-Large Glenn Seaborg were published recently. The Plutonium Story, published by Battelle Press, includes excerpts from Seaborg's diary from 1942 to 1946 and covers his work on the Manhattan Project at the Metallurgical Laboratory of the University of Chicago. The book includes historical annotations and biographical footnotes, describing the lives and careers of participants in the making of the atomic bomb. Modern Alchemy: The Selected Papers of Glenn T. Seaborg, published by World Scientific Press, includes reprints of 105 of Seaborg's scientific papers. Editor's comments add historical perspective to the work on new elements, new isotopes, nuclear medicine and other practical applications, and interpretation of nuclear reactions.

NEW MANAGER FOR DOE-OAK OFFICE:

Martin Domagala has been named the new acting manager of DOE's Oakland Operations Office, replacing Terry Vaeth, who has been reassigned to the DOE operations office in Las Vegas. Domagala will head the 400-person DOE office that oversees the management contracts of LBL, LLNL, SLAC, and the Energy Technology Engineering Center (ETEC) near Simi Valley. Domagala has been with DOE's Bay Area operations office since 1974. He holds a bachelor's degree in social science from Syracuse University, and two master's degrees, one in political science from the State University of New York, and one in public administration from Harvard.

Students glimpse their futures at LBL

By Mike Wooldridge, MAWooldridge@lbl.gov

For many students, summer projects at the Lab are chances to get a first look at the fields they will take on in college and in their career. This year, 26 students are getting that kind of valuable experience through the Center for Science and Engineering Education's Summer Research Program (SRP).

The 10-week program provides summer jobs and activities at the Lab for local high school students from groups underrepresented in science. Organized by CSEE's Marva Wilkins, SRP is in its third year.

Nydia Algazzali, a senior at Berkeley High School, wasn't quite sure what she was getting into when she began her SRP project at the Health Center. "When they told me I'd be working on ergonomics, I said, `Ergo what?' I had no idea what it was," she says. (Ergonomics is the science of designing comfortable, healthy workspaces.)

Algazzali has spent her summer surveying employees who have had their workstations evaluated by Industrial Hygiene over the past two years. The questionnaire asked what part of their workplace had given them problems, what changes had been recommended versus what had been actually implemented, and what they thought of the effectiveness of the ergonomics program. Algazzali's report should help improve the ergonomic programs the Lab offers in the future.

Algazzali chose to work at the Health Center because of her interest in medicine, and has had the chance to practice with some of the tools of the trade while at the Lab. "I've learned how to take a person's blood pressure, and how to take a hearing test in the booth," she says. "I even saw a presentation on EKGs by one of the doctors."

Other SRP students are spending their summer days in less sterile environments. Patricia Ellis, a junior at Castlemont High School in Oakland, is getting acquainted with some of the science that occurs beneath our feet. Ellis is spending the summer participating in the Teacher Enhancement Program, an environmental studies program for high school teachers (and an occasional student). This year the program is focusing on the hydrology of ground water.

Participants have sampled ground water from wells drilled at sites around the Lab, and have learned how to perform pH and conductivity tests to check for water quality and pinpoint pollutants. They also have used topographic maps of the area to predict hydrological movement underground.

"I had learned some about the water cycle in school--about evaporation, condensation and transpiration--but I had no idea what sort of processing water went through before it gets to the faucet," she says. What she has learned about the way water is distilled and purified, she says, should help in her chemistry class in the fall.

Ellis hopes to study environmental science in college and eventually become a science teacher. "I'd like to come back here to work on an environmental project as an undergraduate," she says.

Science isn't the only opportunity open to students at LBL. Helah Jones, a junior at Oakland Technical High School, is spending the summer working in the office of Associate Lab Director Rod Fleischman in the Administration Division, doing filing and other office tasks. "I've definitely had a lot more responsibility here than at any of my past jobs," she says.

Jones has also had the chance to get more computer experience, using word processing programs and spreadsheets. "The people I've worked with have taught me a lot of communication skills, like using the phones and just interacting will people--basic things, but things you need to know in an office."

Jones says she has enjoyed the lectures SRP has arranged for students, which have included talks on career options and journal writing. The highlight , she said, was the talk by Glenn Seaborg, LBL's associate director-at-large. "It was very interesting to hear him talk about his life," she says. "Especially about his work on the first atomic bomb and his experience with the different presidents. It's amazing to think that he worked with Franklin Delano Roosevelt."

Like many of the students, Jones has her future summers already booked with other educational projects. Next year she hopes to travel to Ecuador to participate in a high school program that puts students to work improving health conditions in the third world. She would also like to return to LBL to work on a science or engineering project.

The SRP students will give final presentations on their summer work on Wednesday, Aug. 10, from 9 a.m. to 2 p.m. in the Bldg. 66 Auditorium. All employees are invited to attend.

PHOTO CAPTIONS -- Nydia Algazzali practices taking a blood pressure reading at the Health Center. She helped design an ergonomic survey of Lab employees this summer.

Helah Jones shows some of her day's work to Associate Lab Director Rod Fleischman, in whose office she is working this summer.

Patricia Ellis talks to CSEE's Jose Lopez about a program on ground water science that she is participating in this summer.
Photos by Paul Hames

Ergonomics program gets lift from summer students

Students are not the only ones to benefit from the LBL summer student programs. This summer, much-needed assistance is going to LBL's ergonomics program.

Nydia Algazzali, a Berkeley High School senior (see story above), created an ergonomic survey for employees who have had their workstations evaluated by Industrial Hygiene. Shamly Dhiman, a summer student from the University of Kansas, is also working on the survey. The results may help determine future funding for the program.

Results so far, Algazzali says, show a very favorable response from employees who have used the service--on a scale from one (poor) to five (excellent), three-fourths of employees surveyed rated the program's effectiveness a three or better.

As far as identifying the ergonomic culprits in the average office, chairs were named for causing the most problems, with wrist rests and desks tied for second.

Algazzali and other students in the Summer Research Program will be presenting the results of their projects on Wednesday, Aug. 10, from 9 a.m. to 2 p.m. in the Bldg. 66 Auditorium.

Seaborg Institute gives first postdoctoral award

The Glenn T. Seaborg Institute for Transactinium Science (ITS) announced the selection of the first recipient of the Glenn T. Seaborg Postdoctoral Award this summer.

The recipient, Babak Kadkhodayan, was selected from among some 40 applicants. He received his Ph.D. from UC Berkeley, under the direction of Darleane Hoffman of UCB's Department of Chemistry and LBL's Nuclear Science Division.

Kadkhodayan's doctoral research involved studies of the volatilities of the halides of the transactinide elements rutherfordium (element 104) and hahnium (element 105).

During the past year, Kadkhodayan has been an ITS postdoctoral fellow working on the Waste Isolation Pilot Plant Project and the Yucca Mountain project to examine the behavior of actinides in a variety of environmental media. He began his fellowship on July 1.

The ITS was established to foster the fundamental and applied science and technology of the transactinium elements, which begin with thorium (element 90) and extend through the heaviest element currently known (element 109). The newly established fellowship is funded by the Department of Energy's Office of University and Science Education.

PHOTO CAPTION -- UC Berkeley graduate Babak Kadkhodayan has been selected as the first recipient of the Glenn T. Seaborg Postdoctoral Award.
Photo by Paul Hames

LBL emergency information number

LBL has an out-of-state emergency status announcement number. The number enables employees and their families to verify conditions at the Laboratory following a disaster such as an earthquake, fire, or explosion. The number (at Argonne National Laboratory in Illinois) is:1-800-445-5830.

In the aftermath of a major emergency, employees and their families can call this number to learn of any damage or injury at the Laboratory, and whether it is advisable to come to work or stay away. The recorded message will be updated frequently following such a disaster.

A major disaster in a densely populated area would likely result in severe communication delays. Although local calls may be impossible, out-of-state calls can often be completed. In such circumstances, the main Laboratory number should not be used.

Currents' Flea Market Ad Policy

1. The Flea Market is a service for LBL employees. If space permits, ads will also be accepted from LBL retirees, and employees of LLNL, UC Berkeley, and DOE.

2. The deadline for ads is 5 p.m., Friday, for the following week's issue.

3. Ads must be submitted in writing, by fax (X6641), or e-mail (fleamarket@lbl.gov). No ads will be taken by phone.

4. No ads will be accepted without your name, Lab extension, and home telephone number. You may ask that only one number appear in the ad.

6. Only items of your own personal property may be offered for sale. Ads for material for resale in connection with a business will not be accepted.

7. No ads for services will be taken.

8. Ads will run one week only unless resubmitted in writing. Ads will be repeated only as space permits, and at the discretion of Currents.

Lab to get new copiers with contract renewal

By Brennan Kreller, BKreller@lbl.gov

The Laboratory's copier rental contract with Taylor Made Office Systems expires Dec. 31, and LBL's Procurement group has begun soliciting bids for the next four-year contract.

Under the new contract, which will take effect Jan. 1, 1995, new machines will replace every copier covered by the present contract, even if the contract is awarded to the same vendor.

"The benefit of this is that when a new contract is awarded, the Laboratory can have the use of copiers that incorporate the latest technology available," says Marc Buchalter, a senior buyer in Procurement. "It also helps ensure fair and open competition among all bidders, including the company currently under contract."

Buchalter began compiling information for the request-for-proposals process in January, documenting the copying habits and needs of all the copier users at the Laboratory. This information is passed on to the prospective vendors who try to offer the best and most appropriate package based on that information.

"We consider the Laboratory's needs in terms of speed, capacity, features, delivery, removal, and installation when making the purchase," Buchalter says. "The vendors will know that our goal is to have all 145 copiers replaced with equal or better units one month into the contract period. This includes any training that may be required. Procurement will coordinate the old contractor and the new contractor during the 'swap out' on a copier-by-copier basis to minimize disruption to the users."

A laboratory committee will review the proposals and determine which company offers the best value, including quality and service.

"It's a very detailed process," Buchalter says, "but it allows the Laboratory the opportunity to receive the best-quality products and service. Although every copier has its strengths and weaknesses, having access to the latest technology and negotiating a new contract enables us to make overall improvements for copier users."

Anyone who has questions or suggestions about the copier contract may contact Buchalter at X4500.

PHOTO CAPTION -- BOWLING FOR GOLD -- LBL fire fighter Harold Blair shows off his gold medal from the California State Firefighters' Summer Olympics to Fire Chief Billy White. Blair rolled the top combined score in the bowling event. LBL Firefighters Dave Piepho, Marc Fitzgerald, and Gary Dunbar also competed at the Olympics, held July 17-22 in Palo Alto.
Photo by Paul Hames

LBL softball league

Results of August 3:

Budget Cuts 7, SUDZ 6

Legends 17, Off-The-Hill 7

Rated X 14, Off-The-Hill 2

Animals 17, SUDZ 3

Environ-Mets 13, Ball Park Estimates 11

Native Defects 9, CAMshafts 3

Standings as of August 3:

Western Division

Budget Cuts 7-3

Environ-Mets 6-4

Animals 5-5

SUDZ 4-5

CAMshafts 0-9

Eastern Division

Legends 9-1

Rated X 9-1

Native Defects 3-6

Off-The-Hill 3-7

Ball Park Estimates 2-7

Diversity Committee has new leadership

The Laboratory has announced the appointment of Janet Jacobsen, Earth Sciences Division, and Mary Worth, Life Sciences Division, as the new co-chairpersons of the Laboratory Committee on Diversity. The two will replace Trudy Forte, who chaired the committee from its inception in January 1992 until her recent resignation. The committee also has two new members, Anil More, Environment, Health and Safety Division, and Linda Smith, Information and Computing Sciences Division.

The charge of the Laboratory Committee on Diversity is to provide advice on diversity in the LBL work force, with the aim of more fully integrating diversity into the fabric of the Laboratory's culture, and to provide an environment that is accessible, equitable, and hospitable to all employees.

During the past two years, the Committee's accomplishments have included initial activities for the development of a recruitment brochure to describe career opportunities at LBL; development of a new Recruitment Resource Guide to assist hiring managers in recruiting; formation of an LBL Child Care Center Working group to explore the possibility of establishing an on-site child care center; Laboratory participation in the UC President's Postdoctoral Fellowship Program for postdoctoral fellows from underrepresented groups; development of an LBL/UC Undergraduate Science Fellowship Program to provide mentors for undergraduate students from underrepresented groups; and promotion of the Laboratory's Tuition Reimbursement Program.

Employees are encouraged to contact their representatives on the committee with suggestions regarding diversity-related issues.

COMMITTEE MEMBERS

Co-Chairs: Janet Jacobsen, Earth Sciences Division, and Mary Worth, Life Sciences Division

Gloria Gill, Energy and Environment Division

Joe Kwan, Accelerator and Fusion Research Division

Charles Lawrence, Engineering Division

Zuzanna Lilienthal-Weber , Materials Sciences Division

Grazyna Odyniec, Nuclear Science Division

Roland Otto, Center for Science and Engineering Education

Greg Raymond, Facilities Department

Lonnette Robinson, Physics Division

David Shepherd , Administration Division

Linda Smith, Information and Computing Sciences Div.

Hisao Yokota, Structural Biology Division

Management Liaison: Harry Reed, Office of Work Force Diversity

Student research wrap-up

Students participating in LBL's Summer Research Program will present the results of their projects on Wednesday, Aug. 10, from 9 a.m. to 2 p.m. in the Bldg. 66 Auditorium. All employees are invited to attend.

C A L E N D A R -- August 8 to 12

8 m o n d a y

NUCLEAR SCIENCE DIVISION COLLOQUIUM

4 p.m., Bldg. 70A-3377; S. Bludman, Aspen Center of Physics, "Solar Neutrinos: Present Status and Future Prospects"

PHYSICS DIVISION RESEARCH PROGRESS MEETING

4 p.m., Bldg. 50A-5132; F. Sauli, CERN, "Progress in High-Rate Operation of Microstrip Gas Chambers," Refreshments, 3:40 p.m.

9 t u e s d a y

EH&S CLASS

9 a.m.-noon, Bldg. 90-3148; Lockout/Tagout (EHS-256); pre-registration required, X6612

EH&S CLASS

9:30-11:45 a.m., Bldg. 90-2063; Laser Safety (EHS-280); pre-registration required, X6612

NEW EMPLOYEE WELCOME

10 a.m.-noon, Bldg. 66 Aud.

10 w e d n e s d a y

EH&S CLASS

8 A.M.-noon, Bldg. 2-300F; EH&S Roles & Responsibilities for Supervisors (EHS-25); pre-registration required, X6612

EH&S CLASS

8 a.m.-noon, Bldg. 48-109; First Aid (EHS-116); pre-registration required, X6554

SUMMER LECTURE SERIES

Noon, Bldg. 50 Aud.; M. Bissell, LBL, "Why Do Normal Cells Remember Who They Are, and Cancer Cells Forget? Models to Study Breast Cancer"

EH&S CLASS

1:30-3 p.m., Bldg. 90-4133; Forklift Truck Safety (EHS-225); pre-registration required, X6612

11 t h u r s d a y

SHOEMOBILE

7:30 a.m.- 4:30 p.m., Bldg. 77

LIFE SCIENCES DIVISION SEMINAR

4 p.m., Bldg. 66 Aud.; E. Lee, Univ. of Texas, "Dual Role of the Retinoblastoma Protein in Cell Cycle and in Neuronal Differentiation"

12 f r i d a y

EH&S CLASS

9-11:30 a.m., Calvin Seminar Rm.; Chemical Hygiene & Safety Training (EHS-348); pre-registration required, X6612

EH&S CLASS

10-11:30 a.m., Bldg. 48-109; Fire Extinguisher Use (EHS-530); pre-registration required, X6554

LIFE SCIENCES DIVISION SEMINAR

4 p.m., Melvin Calvin Lab, Seminar Rm. 116; W.-H. Lee, Univ. of Texas, "Regulatory Networks of the Retinoblastoma Protein"

X-RAY SCIENCE & TECHNOLOGY SEMINAR

4 p.m., Bldg. 2-100B; N. Smith, LBL, "Spin-polarized Photoemission and Magnetic Quantum-well States," Refreshments, 3:30 p.m.

Menu

monday

Buckwheat pancakes

Black bean chili

1/2 game hen w/sage dressing

Corned beef & Swiss

South of the Border

tuesday

Corned beef hash & eggs

Chicken vegetable

Pizza

Fishwich

South of the Border

wednesday

3-cheese omelet

Cream of broccoli

Chicken sesame stir-fry

Guacamole burger

South of the Border

thursday

Blueberry pancakes

Oriental chicken w/rice

Baked lasagna

Steakburger & onion rings

South of the Border

friday

Ham scramble

Minestrone

Mediterranean trout

Barbecued beef

South of the Border

F L E A M A R K E T

Flea Market ads may be sent via Lab mail to Bldg. 65B, electronic mail to fleamarket@lbl.gov, or via Fax to X6641. The deadline is 5 p.m. Friday.

AUTOS/SUPPLIES

'68 VW Bug, sunroof, radio/cass., 20K mi. on rebuilt eng., orig. owner, runs great, $1800. William Miller, 642-0653, 525-9197

`72 VW Squarebk, reliable, runs well, gd cond., $1200/b.o. Harvard Holmes, 526-5347

'84 MITSUBISHI Tredia, silver, 4-dr sedan, m/t, p/s, am/fm, perfect int., runs well, $2K. Brian, X5969

'84 ToyoTA Camry LE, 4-dr sedan, a/t, a/c, cruise, runs exc., very reliable, minor cosmetic damage, 103K mi., $2200. Michael, 601-9210

'85 BMW 318i, 2-dr, 5-spd, sunroof, a/c, full power, white, 112K mi., exc. cond., must sell, $6100/b.o. X6333, 524-8183

'87 MAZDA 626 2.0i, a/t, a/c, am/fm cass. stereo, 4-dr sedan, clean, gd cond., $3500/b.o. 793-6844

'89 FORD Taurus, burgundy, 4-dr sedan, a/c, am-fm, p/s, 107K mi., exc. cond, $5300. Jean-Paul Biberian, X5113, 254-7436

MOTORCYCLE, '85 Honda V65 Sabre, Honda fairing, sport bags, well maint., $2600. Jeff Beeman, X5153, 222-5406

TICKETS

49ERS, lower box, 5 yd line, 8/12 vs. Denver, 8/26 vs. Seattle, 3 seats, $39.75 ea. Daryl Horler, X5901, (707)643-2895

TERRY GROSS, 2 tickets for

8/9, $20/both or will trade for 1 ticket to Mon., 8/8 show. Tom, X7882, 682-3966

WANTED

CHILD CARE JOB for my wonderful & very reliable baby-sitter of 2 yrs., exc. refs., Spanish-speaking, ltd. English, 3-4 days/wk, prefer Berkeley, Albany, El Cerrito. Sara, X6614, 849-4175 (eve)

CHILD CARE JOB for my Spanish-speaking baby-sitter,

f/t or p/t, starting Aug./Sept., exc. refs., wonderful, has been working for me since Oct. '92, prefer Berkeley/Albany/Oakland areas. Carolyn, X7827, 631-9781

ELECTRIC MOTOR for my table saw, 2-3 HP 110 volt. Marc, X4500

GARAGE SPACE for storage, secure, dry, prefer Berkeley/Albany/No. Oakland. X4695, 843-5100

HOUSE TO SIT, avail. now to

8/28, for watering, pets, etc., 2 French researchers, responsible. Nathalie & Karine, X4108, 843-3856

INFORMATION on place to stay in Paris for me & my son (9), from 9/16-20 (or 9/22), prefer cent. loc., in a home or house-sitting, could exchange for stay in my 3-bdrm Kensington home in the future. Lynn Price, X6519, 524-2966

LAKE TAHOE RENTAL, 5-7 days, between Christmas & New Years, 2-3 bdrms. Michael Thibodeau, X7626

MOVIE PROJECTOR, 16 MM, and/or editor. Jon, X4462

NORDIC TRACK exerciser, used. 843-6023 (6-8 a.m./p.m.)

PICKUP VOLLEYBALL, Berkeley, Oakland or Emeryville. Mary Kean, X5684, 829-2569

TOOLS, auto & home, for a reasonable price, all types welcomed, screw drivers, wrenches, sockets, jacks, sanders, saws, etc. Robert, X4017, 836-2806

ULTIMATE FRISBEE PLAYERS for a coed corporate league tournament in San Jose, 9/17-18. J. Eto, X7284

MISCELLANEOUS

AIR COMPRESSOR TANK, horizontal 80 gal. cap., tank is 57" long & 20" in dia., w/mounting bracket on top (12" x 31" long), $150. Jack Smith, X5901, 471-4921 (after 3:30 p.m.)

ANTI-GRAVITY "Backswing" brand inversion exerciser for chiropractic therapy, new $350, asking $100. Wendy, X5388, 845-1942

AST 286, 40MB HD, monitor, keyboard, mouse, software, needs work, $300/b.o.; sectional sofa, 6' & 8' units, classic, beige, gd cond., $200. Joan, X5860

BICYCLE for child, very gd cond., $60/b.o. X4138, 525-8807

BICYCLE, 15 low gears (Shimano), 27" wheels, fits persons 5.9" & up, Straight bar (Trekking bike), very comfortable, exc. cond., $180 incl. Kryptonite lock & Cateye halogen light. Armin, X7418, 486-1582

DOUBLE OVEN, elec. Hotpoint, build-in, mustard color, uses 25" cavity, $125/b.o. Dianne, 886-5527

GARAGE, locked, on Coventry Rd. in Kensington, $75/mo. 527-2937 Robert G. Bergman, 642-2156, 642-7714 (FAX)

MOVING SALE: Bicycles, man's 10-spd, 26", sm. frame, $40/b.o.; child's bike, 1-spd, 24" wheels, banana seat, $20/b.o.; kids scooter, hand brakes, $30/b.o.; refrigerator, Sears Kenmore, 24 cu. ft., extra wide door shelves, used 3 yrs., $1K new, avail. 8/10, $450/b.o. Hank, X4517, 673-9716

MOVING SALE: (2) queen sz. mattress w/box spring, $100/ea.; wooden desk, office chair, $30; white wooden dresser, $50; white wooden shelves, $25; mirror, 5 x 5 ft., $15; 2 sm. bedside tables, oak, $10; wooden bookshelf, oak finish, $25; couch, hide-a-bed, $100; 2 matching lamps, ceramic, $15/both; lamp, $5; microwave oven, $45; stereo, $15; bed spreads; sheets; pillows; couch pillows; 2 coffee machines; toaster; popcorn machine; hand mixer; 2 garden chairs; 2 folding chairs; 2 launch chairs; ironing board. Heinz, X4555, 256-4061 (eve.)

NINTENDO SYSTEM w/2 controllers, light gun, six games & cleaner cart., $85; boy's bike, 5-spd, 10" frame, w/child's helmet, $50. Steve, X5064, 655-8379

PERSIAN CARPET, hand-woven, 4'6"x7', very intricate Sarouk from Iran, $1800/b.o. 420-1205

PIANO w/bench, antique tiger oak, 1914 upright, ivory keys, looks & sounds great, $1850. Peter, X7337, 531-7837

REFRIGERATOR, gd cond., white, frost free. Tony, X6470

TENNIS-STRINGING MACHINE, exc. cond., best offer. 642-7055

HOUSING

ALAMEDA, sunny rm w/bay window in spacious, renovated Victorian, custom decorated, modern features, alarm system, built-in vacuum, share w/2 women, pvt. phone & cable, $425/mo. incl. utils. Elise Colson, X4574

ALBANY, 2-bdrm, 2-bth condo, very clean, partly furn., bay view, swimming pool, tennis cts, 24-hr sec., garage parking, bus/BART to LBL/UCB 15 min., nr shopping ctr, no pet, non-smoker, avail Sept., lease, $950/mo. Rai Sun, X7613, 524-7941 (eve.)

ALBANY, 3-bdrm, 1-bth house, kitchen appliances, washer/dryer, hardwd flrs, frpl, detachable garage, lease, $1500/mo., 1st, last + cleaning dep. Kym, 525-8961, 525-8743 (FAX)

BERKELEY, part. furn. 3-bdrm, 1-bth house, recently remodeled, sep. living & dining rms, lg. kitchen, off-st. parking, walking distance to UCB, avail. 9/5, $1200/mo. + dep. May, 642-5025, 843-6129 (eve. until 10 p.m.)

BERKELEY, Elmwood area, furn. 1-bdrm+ flat, sunny, quiet, safe, walk to UCB, split-level, hill view, from lg. terrace, linen, dishes, hi-fi, VCR, microwave, garage, for 1 responsible, mature, neat & non-smoker, prefer visiting scholar, avail. approx. 1 yr. or less, $725/mo. 843-6325

BERKELEY, Ocean View dist., unfurn. studio apt, across st. from lighted tennis cts., parking incl., $435/mo. 540-0385

BERKELEY, Hearst in Ocean View dist., unfurn. studio & 1-bdrm apt, parking & yd incl., $400/studio, $575/1-bdrm. 548-9869

BERKELEY, 2-bdrm house, frpl, yd, garage, workshop, 20 min. walk to UCB/LBL shuttle, $875/mo. 527-4192

BERKELEY, University Terrace Apts, suite in spacious, new, 2-bdrm apt, incl. all household appliances, semi-furn., share w/ present tenant, 10 min. walk from BART/LBL shuttle, $450/mo. + exp. Camilo, X6516, 845-5442

NO. BERKELEY, bed & bkfast, TV, phone line, full kitchen privs., bkfast served 7 days/wk, garden use, walking distance from LBL shuttle/UCB, avail. mid-Aug., $600/mo. incl. utils., by mo. only. 527-3252

EL CERRITO, 2-bdrm apt., nice & save area, bay view, 3 blks from El Cerrito BART station/shops, covered parking, new carpet & oven, coin-op washer/dryer, 1 yr. lease, no pets, $685/mo. Hua, 642-6407, 528-8027

EL CERRITO HILLS, 2-bdrm, 2-bth house, 1200 sq. ft., 6 mi. from LBL, avail. 8/2, $1200/mo. Yu Wong, X5631, 528-0627 (after 6 p.m.)

EL SOBRANTE, part. furn. 2-bdrm, 1-bth condo, pvt. upstairs unit, Parkland view, drive to LBL thru Tilden Pk, pool, tennis, sauna, laundry, $750/mo. Emily, X7979

PIEDMONT, unfurn. 2-bdrm, 1-bth house, hardwd flrs, kitchen, living & dining rms, frpl, garage, storage shack, 15 min. from LBL, exc. schools, no smoking, $1495/mo. 763-7843

RICHMOND ANNEX, 2-bdrm apt in triplex, nr EC Plaza & BART, lg. kitchen, dishwasher, refrig., range, yd, garage w/locked door, coin laundry, new paint & blinds, $695/mo. + dep. Judy, 527-8766

SHARE RENTAL: Female non-smoker environmental engr. looking to share apt/house w/1-3 people in Alameda, Oakland hills or Rockridge area, guys OK, prefer no kids or smokers. Mary, 829-2569

WANTED: 1-bdrm w/2 beds or 2-bdrms for 2 students working at LBL, 8/15-28 in Berkeley. X4108, 843-3856

WANTED: Native Calif. Postdoc relocating to LBL from Switzerland seeks housing (house, studio, apt.) starting 8/4, prefer 2+bdrm, Berkeley, Albany, El Cerrito, Montclair, 2 adult nonsmokers, will care for pets, garden, plants, max. $1K/mo., local refs. avail., desire short (1-2 mo.) or long, term. Greg & Leticia Smestad, (415)979-8730 (msg.)

WANTED: 2-bdrm house in safe, quiet area for 2 quiet, clean, professional women, prefer Northside Berkeley, Rockridge. $900 price range. Laura, X6146

VACATION

CENT. LONDON, furn. 2-bdrm, 1-bth apt, living rm, modern kitchen, cent. heating, carpet, walk to trans., stores, etc., lease, avail Aug. 527-0189

HIGH SIERRAS, comfortable, quiet 4-bdrm cabin, washer & dryer, deck, frpl, hiking, swimming, fishing, canoeing (comes w/house), sunbathing, 4 hr from Berkeley, 1 hr from Truckee, wks/wkends, to those who will take gd care of our vacation home. Jane Mauldon, 642-3475, 849-4096

SO. LAKE TAHOE, lakefront townhouse, all amenities, nr all playspots. Herbert Newkirk, 422-8845, 455-5595

FOR FREE

CAT, gentle adult female calico, indoor/outdoor, our son has asthma, so we need to find a good home for her. Lindsay, X5009, Vern, X7504, 528-2951

DOG, 5 yr. old miniature wire hair dachshund, to gd home. Mary or Don, X7461, 582-3079, 539-7900

Currents Staff

EDITOR:

Mary Bodvarsson, X4014

Mac QuickMail, fax X6641

mabodvarsson@lbl.gov

STAFF WRITERS:

Jeffery Kahn

Mike Wooldridge

Lynn Yarris

CALENDAR:

Fax X6641

currents_calendar@lbl.gov

Deadline: 10:30 a.m. Tuesday

FLEA MARKET:

Fax X6641

fleamarket@lbl.gov

Deadline: 5 p.m. Friday

INFORMATION:

Mary Padilla, X5771

PRODUCTION:

Alice Ramirez

PUBLISHED WEEKLY BY THE

Public Information Dept., Bldg. 65B

Mike Chartock, Acting Manager