LBL chemists in the Structural Biology Division have produced the first 3-D image of an RNA structure that plays a vital role in enabling retroviruses to replicate within cells.
The structure, a double-looped strand of RNA that forms what is called a "pseudoknot," was revealed to contain a bend in its shape that may serve as the site where key host proteins interact. It may be possible, the researchers say, to design drugs that could fight retroviruses--the most notorious of which is HIV--by binding to the pseudoknot at this site and blocking these interactions.
The research was reported in the April 14 issue of the Journal of Molecular Biology, in a paper co-authored by Ignacio Tinoco, Jr., who is also a professor of chemistry at UCB, and his student, Ling X. Shen.
A retrovirus is a protein-coated packet of RNA (ribonucleic acid) that requires the chemicals of a host cell to make viral DNA and proteins from its RNA genome. When a retrovirus invades a cell it synthesizes three enzymes: integrase, protease, and reverse transcriptase. These enzymes enable it to transform the host into a virus replication factory. The mechanism by which this enzyme synthesis is carried out is called "ribosomal frameshifting" and involves a shift in the order in which the virus's RNA genetic code is read. Retroviruses use a "minus-one" frameshift, which means the reading of the code starts one nucleotide from where it should.
"The efficiency of frame-shifting is modulated by messenger RNA structures such as a pseudoknot downstream of the frameshift sight," says Tinoco. "The minus-one frameshifting translational mechanism allows controlled synthesis of viral enzymes and structural proteins."
To understand how pseudoknots promote frame-shifting, scientists need detailed structural information. Tinoco and Shen, working in collaboration with the UC San Francisco group of Harold Varmus (head of the National Institutes of Health), used nuclear magnetic resonance (NMR) spectroscopy to produce a 3-D, high-resolution image of a 34-nucleotide pseudoknot that is known to cause high-efficiency frame-shifting in the mouse mammary tumor virus.
In NMR spectroscopy, atomic nuclei are identified and spatially located by their characteristic absorbence of radiowaves in a magnetic field. Tinoco is one of the few researchers to use NMR to study RNA, which is the workhorse of the genetic world. It transcribes the coded instructions of DNA and assembles amino acids into proteins. In 1992, Tinoco led a research team that produced the first 3-D image of a stem-loop "hairpin," a common and highly stable RNA structural element with critical folding and protein-recognition properties.
"When the loop of a stem-loop hairpin pairs with a complementary sequence outside the loop to form a second stem, the resulting structure becomes a pseudoknot," Tinoco says. The structure is only partially twisted, otherwise it would form a knot.
From their NMR images, Tinoco and Shen discovered that the presence of the nucleotide adenine at the junction of the two stems of the pseudoknot derived from the mouse mammary tumor virus creates a bend in the shape of the pseudoknot. Subsequently, the Tinoco and Varmus research groups experimented with modifying the pseudo-knot's nucleotide sequences. The idea was to find out which sequences resulted in frame-shifting and which did not.
They found that with the bend in its shape, the pseudoknot promotes high-efficiency (up to 20 percent) frameshifting. If the intervening adenine nucleotide is removed, a pseudoknot is formed without a bend and no frameshifting occurs. The next step will be to find which ribosomal proteins recognize this bend and interact with it in order to frameshift.
"Our NMR data indicate that there are internal dynamics associated with the pseudoknot," says Tinoco. "The unique, compact structure and conformational flexibility of the pseudoknot may be required for recognition and favorable interaction with the translating ribosome, or with the translation factors associated with the ribosome."
Poppe, 58, will work with King and Walter Massey, UC provost and senior vice president for academic affairs, in overseeing a broad range of activities related to the University's academic and programmatic relationship with the three UC-managed DOE labs (LBL, LLNL, and Los Alamos National Lab). In addition, Poppe will work closely with King in his overall responsibilities related to UC's research efforts.
The University's academic and programmatic oversight of the laboratories includes increased coordination with DOE; enhanced communication with other agencies and Congressional entities; coordination of the activities of the UC President's Council on the National Laboratories; and the recommendation of UC policies and positions regarding laboratory issues.
One of Poppe's major responsibilities will be to guide and promote the collaborative research activities and opportunities among the three DOE laboratories, UC's nine campuses, the larger scientific community, and private industry.
"This position is another step in the change that is taking place in the University in its oversight of the laboratories and reflects the importance that the University places on fostering increased collaboration between the campus and the laboratories," Poppe said of the new post.
A nuclear physicist, Poppe returned to LLNL last year after two years on special assignment to DOE's Washington, D.C., headquarters as a technical advisor in the Office of Arms Control and Nonproliferation. In 1992 and 1993, as a DOE delegate and scientific advisor, he participated in two U.S. delegations to the Joint Compliance and Inspection Commission of the START Treaty in Geneva, Switzerland.
With Poppe's appointment, Tommy Ambrose, who had been UC acting special assistant for laboratory affairs, will return to the Livermore laboratory as the University's liaison officer.
Height (m)* Small Frame (kg)+ Medium Frame Large Frame
1.57 58.1 - 60.8 59.4 - 64.0 62.6 - 68.0
1.60 59.0 - 61.7 60.3 - 64.9 63.5 - 69.4
1.63 59.9 - 62.6 61.2 - 65.8 64.4 - 70.8
1.65 60.8 - 63.5 62.1 - 67.1 65.3 - 72.6
1.68 61.7 - 64.4 63.0 - 68.5 66.2 - 74.4
1.70 62.6 - 65.8 64.4 - 69.8 67.6 - 76.2
1.73 63.5 - 67.1 65.8 - 71.2 68.9 - 78.0
1.75 64.4 - 68.5 67.1 - 72.6 70.3 - 79.8
1.78 65.3 - 69.8 68.5 - 73.9 71.7 - 81.6
1.80 66.2 - 71.2 69.8 - 75.3 73.0 - 83.5
1.83 67.6 - 72.6 71.2 - 77.1 74.4 - 85.3
1.85 68.9 - 74.4 72.6 - 78.9 76.2 - 87.1
1.88 70.3 - 76.2 74.4 - 80.7 76.2 - 87.1
1.91 71.7 - 78.0 75.7 - 82.5 79.8 - 91.6
1.93 73.5 - 79.8 77.6 - 84.8 82.1 - 93.9
Height (m)* Small Frame (kg)+ Medium Frame Large Frame* Multiply your height (in inches) by 0.0254 to get your height in meters.
1.47 46.3 - 50.3 49.4 - 54.9 53.5 - 59.4
1.50 46.7 - 51.3 50.3 - 55.8 54.4 - 60.8
1.52 47.2 - 52.2 51.3 - 57.1 55.3 - 62.1
1.55 48.1 - 53.5 52.2 - 58.5 56.7 - 63.5
1.57 49.0 - 54.9 53.5 - 59.9 58.1 - 64.9
1.60 50.3 - 56.2 54.9 - 61.2 59.4 - 65.8
1.63 51.7 - 57.6 56.2 - 62.6 61.2 - 68.5
1.65 53.1 - 59.0 57.6 - 64.0 62.1 - 70.3
1.68 54.4 - 60.3 59.0 - 65.3 63.5 - 72.1
1.70 55.8 - 61.7 60.3 - 66.7 64.9 - 73.9
1.73 57.1 - 63.0 61.7 - 68.0 66.2 - 75.7
1.75 58.5 - 64.4 63.0 - 69.4 67.6 - 77.1
1.78 59.9 - 65.8 64.4 - 70.8 68.9 - 78.5
1.80 61.2 - 67.1 65.8 - 72.1 70.3 - 79.8
1.83 62.6 - 68.5 67.1 - 73.5 71.7 - 81.2
+ Multiply your weight (in pounds) by 0.4536 to get your weight in kilograms.
The Performance Management Refresher will review and highlight the key elements in the P2R process, including the writing of the position description, for managers and supervisors who have already taken the full workshop.
Workshop dates are as follows:
Call EDT at X5999 for enrollment information.
Harvey Gould, a senior physicist in the Chemical Sciences Division, has been elected secretary-treasurer of the Precision Measurement and Fundamental Constants Topical Group of the American Physical Society, for a 3-year term to begin April 27. The 500-member group promotes research and education in precision measurements, measurements of fundamental constants, and tests of fundamental laws (symmetry, quantum electrodynamics, gravitation, etc.) through sponsorship of symposia, conferences, awards, the publication of a newsletter, and other professional activities.
LBL HEADED FOR DOS?
New House Science Committee Chair Robert Walker (R-PA), has announced his intention to introduce legislation that would combine much of the federal government's non-medical civilian research into a single U.S. Department of Science (DOS). Walker, considered a strong supporter of science, says this will boost the prestige of scientific research while lowering the cost. The proposed DOS would include four agencies--Department of Energy, Environmental Protection Agency, National Aeronautics and Space Administration, and National Science Foundation--plus the five science organizations in the Commerce Department (National Oceanic and Atmospheric Administration, National Institute of Standards and Technology, Patent and Trademark Office, National Technical Information Service, and National Telecommunications and Information Administration), and the Interior Department's U.S. Geological Survey. According to figures from the Office of Management and Budget, if these agencies were combined, the work force and budget would total about 78,000 employees and $46 billion.
Critics say such numbers present a target that would be all too vulnerable to budget-cutters. They say pulling science out of mission agencies would weaken its contribution to the national economy. The same critics argue that having separate funding sources has helped science make rapid progress in several fields. Still others worry that despite Walker's support for science, some of his colleagues will use his proposal as a "smoke screen" to kill research programs.
UNCLE SAM WANTS YOU:
Congress and the Clinton Administration may be waging a race to see who can shrink government faster, but federal agencies continue to provide jobs for scientists at a faster rate than for other white-collar occupations. Figures from the National Science Foundation show that between 1989 and 1993, the number of scientists employed by the federal government rose by 13.2 percent. Most of that growth came in such areas as data collection, administration, resource management, and technical assistance. For those involved in R&D, the growth in jobs was 2.3 percent--slower than the 3.1 percent increase for the entire work force, but faster than the 1 percent for all government white-collar workers. The Defense Department was the only agency to show a decline in science jobs during that period.
U.S. HOLDS LEAUD IN TECHNOLOGY RACE:
The National Critical Technologies Report, recently issued by the Office of Science and Technology Policy, shows the United States even with or ahead of both Japan and Europe in 27 key technological areas. The report shows the U.S. to hold a substantial lead over all its competitors in many fields in information and communication, materials, and transportation. The U.S. is also leading the way in the medical, biotech, agriculture, and food technologies. In the energy and environmental quality fields, as well as the manufacturing fields, however, the U.S. lead is marginal and eroding. One Congressional expert has noted that previous versions of the Critical Technologies Report have had little direct influence on policy or research dollars, but have proven helpful to Congressional lobbyists for getting more money for special-interest industry consortia.
When Doug Herring entered a national photo contest in 1990, it was the first time he had shared his travel photographs with anyone besides his family and friends. He ended up taking the $1,000 first prize.
The winning entry, titled "After Prayers," was taken at a Buddhist monastery in Thailand. It was also featured as a two-page spread in Natural History magazine in June of that year.
Now cultivating his interest in travel photography much more intently, Herring has "After Prayers" and 19 other photos on display at Restaurant Porcini (1843 Solano Ave.) in Berkeley. The showing has been extended through May 27.
Herring is an environmental analyst for the NEPA/CEQA Program (National Environmental Policy Act/California Environmental Quality Act) in the Office for Planning and Communications. Although a master's degree in public policy led him to a career in environmental analysis, he says his fascination with other cultures has persisted.
Herring began to record his overseas experiences on film in 1980, while working as an electrical theory and wiring instructor with the Peace Corps in Morocco. He continued his hobby when he re-enlisted and served a second two-year stint as a malaria control trainer in Thailand.
"I was fascinated by these cultures, and I just wanted to document my experiences," he says. "I learned that I enjoyed photography quite incidentally. And although many of my photos are of people, I would never ask anyone to pose for me. I just happened to catch them at the right moment."
In addition to Morocco and Thailand, Herring has documented his travels to Nepal, Indonesia, Turkey, and Greece. More recently, he has included shots of California scenery acquired during backpacking trips in the Sierras.
Since winning the contest in 1990, Herring has taken his photography more seriously, holding several exhibits in the Bay Area, and producing greeting cards which he sells to local shops. And whenever he travels now, he makes certain to take lots of film.
The Health Services Department is now offering tuberculosis (TB) screening at LBL. All employees are encouraged to take advantage of this service. To make an appointment, call X6266.
Want to stop smoking?
The American Cancer Society is offering a Smoking Cessation Course to be held at LBL. The cost is $20 per person. A minimum number of people are needed to offer the class, so you are encouraged to call Health Services at X6266 if you or someone in your immediate family would like to quit smoking. The six-session course runs five weeks.
The artist will visit the Laboratory on Friday, April 21, to give a noontime talk on "Public Art: A Pathway to Our Natural Heritage" in the Bldg. 50 Auditorium.
All employees are invited to attend.
Here is how it works: You may exchange any package of seeds that you bring in for a package of seeds brought in by someone else. If the seeds are not in their original package or if you're bringing in seeds that you've collected from your garden, be sure to include a description of the plant and planting and growing instructions.
The advantages of electronic mail are obvious. It is fast and paperless. Less obvious are some ways of using e-mail efficiently. Below are some tips on e-mail etiquette, supplied by ICSD's Russ Montello.
Sadie's Early Bird: Two eggs, two bacon, two toast w/coffee $2.95
Soup of the Day: Vegetarian split pea(TM) reg. $1.35 lg. $1.95
Bistro Fare: Roast pork roast, whipped potatoes
& gravy w/succotash $3.95
Passports: South of the Border a la carte
Sadie's Grill: Chicken Santa Fe w/spicy fries(TM) $3.75
Sadie's Early Bird: Biscuit & gravy w/eggs $2.60
Soup of the Day: Hearty beef barley reg. $1.35 lg. $1.95
Bistro Fare: Pesto & spinach lasagna w/cheese
focaccia bread(TM) $3.95
Passports: South of the Border a la carte
Sadie's Grill: Fishwich & fries $3.25
Sadie's Early Bird: Breakfast sandwich w/hash browns $2.95
Soup of the Day: Pork mulligatawny reg. $1.35 lg. $1.95
Bistro Fare: Chicken sesame stir-fry over rice(TM) $3.95
Passports: South of the Border a la carte
Sadie's Grill: Sloppy Joe w/fries $3.25
Sadie's Early Bird: Blueberry pancakes w/coffee $2.05
Soup of the Day: Manhattan clam chowder reg. $1.35 lg. $1.95
Bistro Fare: Savory baked cod w/twice baked
potatoes & vegetable(TM) $3.95
Passports: South of the Border
Sadie's Grill: Philly cheese steak & fries $3.95
Sadie's Early Bird: Ham scramble $2.60
Soup of the Day: Chicken-corn chowder reg. $1.35 lg. $1.95
Bistro Fare: Pasta Piatti(TM) $3.95
Sadie's Grill: Guacamole burger w/spicy fries $3.75
*Denotes recipe lower in fat, calories & cholesterol
17 m o n d a y
MATERIALS SCIENCE AND ENGINEERING SEMINAR
"Formation of Intermetallic Phases at Interfaces" will be discussed by Katy Barmak of Lehigh University at 9 a.m. in 458 Evans.
THEORETICAL PHYSICS SEMINAR
"Nonfactorization in B and D Decays" will be presented by Abdul Kamal of the University of Alberta, Canada, at 2:30 p.m. in 430 Birge.
CHEMICAL ENGINEERING COLLOQUIA
"Mass Transport Around Microprofiles" will be presented by Gerhard W. Matzen, Ph.D. candidate; "Molecular Modeling of Methane Diffusion in Glassy Atactic Polypropylene Using Highly Multidimensional Transition State Theory" will be presented by Michael L. Greenfield, Ph.D. candidate, at 3:30 p.m. in the Pitzer Auditorium, Latimer; refreshments at 3 p.m.
PHYSICS DEPARTMENT COLLOQUIUM
"Topological Orders and Edge States in Fractional Quantum Hall Liquids" will be presented by Xiao-Gang Wen of MIT at 4:30 p.m. in 1 Le Conte; tea at 4 p.m. in 375 Le Conte.
18 t u e s d a y
Introduction To Environment, Health & Safety At LBL (EHS 10), 9-11:30 a.m., Bldg. 66 Auditorium.
Lockout/Tagout Training (EHS 256), 9-11:30 a.m., Bldg. 48-109. Call X6612 to register.
Laser Safety (EHS 280), 9:30 a.m.-noon, Bldg. 90-2063. Call X6612 to register.
LESBIAN, GAY AND BISEXUAL ASSOCIATION MEETING
Noon, Bldg. 90-2063
19 w e d n e s d a y
Adult CPR (EHS 123), 9 a.m.-noon, Bldg. 48-109. Call X6554 to register.
Recertification Crane/Hoist (Level 1) Operator Training (EHS 216), 8 a.m.-noon, Bldg. 70A-3377. Call X6612 to register.
The LBL Eco-Fair will be held from 11:30 a.m.-1:30 p.m. on the cafeteria lawn and parking lot. Participants include: Sierra Club, Berkeley TRiP, California Native Plant Society and in-house groups such as E&E, Bicycle Coalition, Waste Minimization and the Green Team.
ENERGY & RESOURCES GROUP COLLOQUIUM
"The Biopolitics of Fish in the San Francisco Bay-Delta Estuary System" will be discussed by Peter Moyle of UCD at 4 p.m. in 2 Le Conte; reception at 3:30 p.m. in 100A, Bldg. T-4.
20 t h u r s d a y
THE MATERIALS SCIENCES DIVISION SCIENCE FOR SUPPORT STAFF LECTURE
"The Motorcycle as a Vehicle for MSD Research" will be presented by Jeff Reimer of LBL at 11 a.m. Bldg. 66-316.
Various local organizations will be sharing information pertaining to health issues from 11:30 a.m.-2 p.m. in the cafeteria; sponsored by the Health Services Nurse Mentoring Program.
SURFACE/CATALYSIS SCIENCE SEMINAR
"The Causes and Consequences of Epitaxial Roughness" will be presented by A. Zangwill, Georgia Institute of Technology, at 1:30 p.m. in the Bldg. 66 Auditorium.
MATERIALS SCIENCE SEMINAR
"Boundaries in Superconducting Oxides: Friends or Foes?" will be presented by Siu-Wai Chan of Columbia University, at 4 p.m., 105 Northgate.
PHYSICS DIVISION RESEARCH PROGRESS MEETING
"An Overview of the Physics of Extended Gauge Sectors" will be presented by Thomas Rizzo of SLAC, at 4 p.m., Bldg. 50A-5132; refreshments at 3:40 p.m.
21 f r i d a y
CENTER FOR BEAM PHYSICS SEMINAR
"Lie Methods for Ray and Wave Optics" will be presented by Alex Dragt of the University of Maryland, at 10:30 a.m. in the Bldg. 71 conference room.
EARTH MONTH LECTURE
"Public Art: A Pathway to our Natural Heritage" will be presented by Erica Fielder of the California Coastal Conservancy at noon in the Bldg. 50 Auditorium.
BIOMECHANICAL ENGINEERING SEMINAR
"Bioresorbable Biomaterials" will be presented by Hari Dharan of UCB at 1 p.m. in 3110 Etcheverry.
24 m o n d a y
OPEN HOUSE COORDINATOR'S MEETING
10:30 a.m.-noon in the Bldg. 50 Auditorium.
CHEMICAL ENGINEERING COLLOQUIA
"Selective Recovery of Propylene Glycol from Dilute Aqueous Solutions Using Complexation or Reversible Chemical Reaction" will be presented by Robert R. Broekhuis, Ph.D. candidate; "Mechanistic Study of Zeolite Synthesis from Silicate Gels Containing Ammonium Cations" will be presented by Craig S. Gittleman, Ph.D. candidate, at 3:30 p.m. in the Pitzer Auditorium, Latimer; refreshments at 3 p.m.
PHYSICS DEPARTMENT COLLOQUIUM
"B Mesons: The New Hydrogen" will be presented by Persis S. Drell of the Cornell University at 4:30 p.m. in 1 Le Conte; tea at 4 p.m. in 375 Le Conte.
25 t u e s d a y
Back Injury Prevention (EHS 53), 9:30-11:30 a.m., Bldg. 51-201. Call X6612 to register.
SUTTA COMPANY TOUR
The second tour of the Sutta Company, the Lab's recycler, will be held from 11:30 a.m. to 1:15 p.m. Call X6123 to register.
26 w e d n e s d a y
EH&S Roles & Responsibilities for Supervisors in Research Settings (EHS 25), 8:30 a.m.-noon, Bldg. 90-2063, concludes on Friday. Call X6612 to register.
EARTH MONTH LECTURE
"Water Cycles and the Bay" and "Industrial Pollution Prevention" will be discussed by the Regional Water Quality Control Board at noon in the Bldg. 50 Auditorium.
Build confidence and learn to effectively organize and present your ideas in a friendly, supportive atmosphere, 12:10-1 p.m., Bldg. 2-100.
ENERGY & RESOURCES GROUP COLLOQUIUM
"EBMUD's New Board: Environmental Implications" will be discussed by Laura King of EBMUD, at 4 p.m., 2 Le Conte; reception at 3:30 p.m. in 100A, Bldg. T-4.
27 t h u r s d a y
DAUGHTERS TO WORK DAY 1995
DEPARTMENT OF ASTRONOMY COLLOQUIUM
"The Search for Curvature of Space" will be presented by Allan Sandage of Carnegie Observatory, at 3:30 p.m. in 2 Le Conte; tea at 3 p.m., 661 Campbell.
MATERIALS SCIENCE SEMINAR
"Chemical Vapor Deposition of Thin Metal Films: Research and Applications" will be presented by Frances Houle of the IBM Almaden Research Center, at 4 p.m., 105 Northgate.
28 f r i d a y
EH&S Roles & Responsibilities for Supervisors in Research Settings (EHS 25), 8:30 a.m.-noon, Bldg. 90-2063, continued from Wednesday. Call X6612 to register.
Call Lawrence Hall of Science at 642-5132 for more information, or 642-5134 for camp registration.
'65 FORD Mustang, 63K mi., many items, all orig., $5K firm. Michael, 215-8186
'82 FORD Club wgn van, 7-pass., 351-c.i. V-8, 127K mi., blue/white, new smog cert. gd 90 days, $3K/b.o. Sergio, X5457, (707)429-2575
'82 HONDA Civic, 5-spd, driveable but needs radiator & head gasket, many new parts, gd shape, $500. Ellen, X5062
'85 PORSCHE 944, red w/blk int., sun roof, low mi., $5900. Russ, 339-9812
'87 PONTIAC(GM) Bonneville, silver gray, 4-dr sedan, fuel injection, a/t, p/s, a/c, am/fm, 96K mi., new brakes, $2600. Hiroshi, X4581
'93 MIATA, white, 23K mi., a/c, stereo, p/s, golf/bike attachment, cover, $15.5K/b.o. Tom Kutz, X4590, (707)447-1310
BED LINER, like new, fits on a Ford XLT short bed truck, $285 new, $150. 278-7967
TIRES w/cast aluminum rims, Firestone Wilderness AT P265/75R15, brand new, $600 for the complete set. 278-7967
CLASSICAL GUITAR, elec. keyboard, music stand, footrest, classical guitar music. Chuck, X4461, 521-6368
WEED WHACKER. Doug, X6626, 626-4644
BOAT, '79, 16 ft., i/o Bowrider, fish/ski, $2500. 656-3011
PRINTER, Macintosh Stylewriter II, exc. cond., still under warranty, $220/b.o. 524-9039
ROAD BIKE,12-spd Centurion, finger-tip shifters, 25-in cro-moly frame, $100/b.o. Doug, X6626, 526-4644
SECTIONAL SOFA , 2-pc., 8' & 6', beige, gd cond., $175. Joan, X5860
SOFA BED; 6 antique dining chairs, newly upholstered. Joseph, 642-2496, 530-3475
SOFA/COUCH, Lazy Boy, almost new, $350/b.o.; Lazy Boy rocker/recliner, $50; sofa, 8', $50; Levelor mini blinds, brn, $20 ea./b.o. Bob, X4580, 229-5549
ALBANY, furn. rm in pvt home, sep. ent., pvt bth, kitchen privs., share washer/dryer, nr trans. & shops, quiet non-smoker, avail. 6/18, $450/mo. incl. utils. 526-2355
ALBANY, 2-bdrm, 2-bth condo., bay view, tennis cts., pool, sauna, gym, 24 hr. sec., indoor garage, avail. 6/1, $975/mo. 631-0510
ALBANY, 1-bdrm apt in 4-plex, refrig., stove, oven, drapes, carpet & hardwd flr in bdrm, no pets, yr. lease, 2 blks from El Cerrito Plaza/BART, $625+$800 dep. Tom/Judy, 527-8766
ALBANY, Garfield between Kains & San Pablo, 3 rm studio apt, $550/mo. (415)775-3889
BERKELEY, sm. studio apt, skylight, sunny kitchen, wood flrs, can be furn., sm. garden, nr gourmet ghetto, 15 min. walk to UC/LBL shuttle, avail. 4/15, $525/mo. 540-0385
BERKELEY, 1-bdrm apt, parking, sm. garden, 20 min. walk to UC/LBL shuttle, nr shops, BART & park, avail. 5/1, $535/mo. 548-9869
BERKELEY, sm. furn. studio apt, Ocean View area, nr 4th St. shops & cafes, close to bus, $485/mo. 540-0385
BERKELEY, Northside, share lg., unfurn. 2-bdrm apt w/quiet, older U.C. grad student, wood flrs, sep. dining rm, living rm, lg. kitchen w/gas stove, washer/dryer, 2 blks to LBL bus stop, $475/mo. + 1/2 PG&E + your own phone. Andy, 204-9685
BERKELEY HILLS, furn. 2.5-bdrm, 2.5-bth house, frpl, avail. 9/1/95 - 6/31/96, $800/mo.+utils.+dep. 642-3577
BERKELEY HILLS, furn. 1-bdrm, 1-bth apt, remodeled, nr shops & trans., non-smoker, avail. June, $850+utils. 524-9039
NO. BERKELEY, furn. 3-bdrm, 2-bth home, study, yd, nr Solano shops & buses, hot tub, deck, bay view, car/bikes avail., avail. 7/1 - 12/28, $1500/mo. X7127, 524-0305
NO. BERKELEY, furn. 1-bdrm penthouse, kitchen appliances, TV, dbl bed (linen & towels incl.), ofc. w/leather sofa, elec. entrance, 1-1/2 blks from UCB, LBL shuttle, public trans., shopping, etc., garden, patio, laundry rm, st. parking, or sec. parking w/fee, 1 or 2 people max., no pets, no smoking, avail. 5/21, $1200+dep. 548-8658, 548-6528 (FAX)
EL SOBRANTE, 3-bdrm, 2-bth house to share w/1 other person, quiet, rural neighborhood, 8 mi. north of Berkeley, 12 mi. to UCB, hot tub, frpl, washer/dryer, pvt bath, pvt phone line, sep. work/study space, sunny yd, garden, clean, quiet, responsible, no pets, no smoking, gd refs., $425/mo.+share utils. 222-1361 (eve./msg.)
HERCULES, 3-bdrm 2.5-bth condo, 2-car garage, nr park, lease option to buy $1370/mo. or assume loan $139K/5% down. 799-0818
KENSINGTON, furn. in-law studio, quiet, pvt entrance, patio, non-smokers, short term OK, avail. 5/1, $475/mo. incl. utils. 559-8021
KENSINGTON, 2-bdrm, 1-bth house, yd, deck, hardwd flrs, lg. modern kitchen, laundry, garage, frpl, 3.5 miles from LBL, nr shops & trans., avail. mid-May to Aug. w/yr. lease from Aug. option, $1290/mo.+utils. Erik, X4446, 526-1369
OAKLAND, 2-bdrm top-floor flat, Adam's Point, walk to BART/Grand Ave., quiet non-smoker(s) pref., $750 incl. util.+dep. 268-0674
YOKOHAMA, JAPAN, 2-bdrm condo., can commute to Tokyo/Yokohama downtown, avail. now thru 8/31 (negot.). X4414, 525-9432
WANTED: 2-bdrm house/apt for visitor to lab, 7/13 - 9/9 flexible after 9/1. Henry Stapp, X4488
WANTED: For Norwegian visitor & family (2 sm. children), 2-3 bdrms, 8/1/95-6/1/96. Lydia, 642-5464
WANTED: For Norwegian visitor & family (possibly 4 children, 2 adults), furn. 3+bdrms home, 8/1/95-6/1/96. Lydia, 642-5464
WANTED: Anything from 2-bdrm apt to house for responsible, non-smoking, middle-aged couple, 8/15-1/1 (flex.). Luanne, X5853
WANTED: Furn. 2-bdrm house for family from Japan, 8/1-31, prefer in Berkeley or nearby & nr trans. (415)331-6742
WANTED: Summer sublets, 6/4 - 8/13, for LBL Summer Research Program students. Mari Shine, X5437
EL CERRITO, nr Fatapple's, 2-bdrm, 1-bath house, quiet, gd neighborhood, lg. backyd, frpl, move-in cond., $209K. Ashok, X4651, 524-5723
SO. LAKE TAHOE, deluxe townhouse, lakefront, all amenities, nr all play spots. Herbert, 422-8845, 455-5595
Mary Bodvarsson, X4014
Jeffery Kahn, X4019
Diane LaMacchia, X4015
Mike Wooldridge, X6249
Lynn Yarris, X5375
Brennan Kreller, X6566
Mary Padilla, X5771
Public Information Department
LBL, MS 65 (Bldg. 65B)
One Cyclotron Rd.
Berkeley, CA 94720
Tel: (510) 486-5771
Fax: (510) 486-6641
LBL is managed by the
University of California
for the U.S. Department of Energy