publications

 


Pelissier FA, Garbe JC, Ananthanarayanan B, Miyano M, Lin CH, Jokela T, Kumar S, Stampfer MR, Lorens JB, LaBarge MA. Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors. Cell Reports (2014)


Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai YA, Gartner ZJ. Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding. Tissue Eng Part C Methods (2014)


Garbe JC, Vrba L, Sputova K, Fuchs L, Novak P, Brothman AR, Jackson M, Chin K, LaBarge MA, Watts G, Futscher BW, Stampfer MR. Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Cell Cycle (2014)


LaBarge MA, Parvin B, Lorens JB. Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics. Adv Drug Del Rev (2014)


Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, LaBarge MA, You L, Kogan SC, Gray JW, Mao JH, and Wei G. CUL4A induced epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Research (2014)


LaBarge MA. Breaking the canon: Indirect regulation of Wnt signaling in mammary stem cells by MMP3. Cell Stem Cell (2013)


Sputova K, Garbe JC, Pelissier FA, Chang E, Stampfer MR, and LaBarge MA. Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length. Genome Integrity (2013)  May 29;4(1):4


LaBarge MA, Garbe JC, and Stampfer MR. Processing of human reduction mammoplasty tissues for cell culture. Journal of Visualized Experimentation (2013) Jan3;(71) - VIDEO ONLINE


Lin CH, Lee JK, and LaBarge MA. Fabrication and use of MicroEnvironment microArrays (MEArrays). Journal of Visualized Experimentation (2012) Oct 11 - VIDEO ONLINE


Liu JS, Farlow JT, Paulson AK, LaBarge MA, and Gartner ZJ. Programmed cell-to-cell variability in Ras activity triggers emergent behaviors during mammary epithelial morphogenesis. Cell Reports (2012) Oct 3 [epub ahead of print]

PMID: 23041312

Garbe JC, Pepin F, Pelissier FA, Sputova K, Guo DE, Villadsen R, Park M, Petersen OW, Barowsky A, Stampfer MR, and LaBarge MA. Aging is associated with increased multipotent progenitors with a basal differentiation bias in human mammary epithelia. Cancer Research (2012) [epub ahead of print] In press   RELATED ARTICLE#1 RELATED ARTICLE #2


LaBarge MA. On Stem Cells in the Human Breast. Cold Spring Harbor Perspectives in Biology. (2012):a013441


Chanson L*, Brownfield D*, Garbe, JC, Kuhn I, Stampfer MR, Bissell MJ, and LaBarge MA. Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells. PNAS (2011), 108(8)3264-9. RELATED ARTICLE


LaBarge MA. The difficulty of targeting cancer stem cell niches. Clinical Cancer Research, Jun (2010), 16(12):3121-9


LaBarge MA, Nelson CM, Villadsen R, Ruth J, Stampfer MM, Petersen OW, and Bissell MJ. Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments. Integrative Biology, Jan (2009).1(1):70-9 Epub 2008 Nov 12 RELATED ARTICLE


LaBarge MA and Bissell MJ (2008). Is CD133 a marker of colon cancer stem cells? The Journal of Clinical Investigation. Jun;118(6):2021-4.


Radisky D and LaBarge MA (2008). Epithelial-Mesenchymal Transition and the Stem Cell Phenotype. Cell Stem Cell. Jun 5;2(6):511-2


LaBarge MA, Petersen OW, and Bissell MJ. (2007). Of Microenvironments and Mammary Stem Cells. Stem Cell Reviews. 2007 Jun;3(2):137-46.


Villadsen R, Fridriksdottir AJ, Gudjonsson T, Rank F, Rønnov-Jessen L, LaBarge MA, Bissell MJ, and Petersen OW (2007). Evidence for a stem cell hierarchy in the adult human mammary gland. Journal of Cell Biology, Apr 9;177(1):87-101


Bissell MJ, LaBarge MA. (2005). Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?  Cancer Cell, January; 7(1):17-23.